Mass spectrometry (MS) has become the tool of choice for the large scale identification and quantitation of proteins and their post-translational modifications (PTMs). This development has been enabled by powerful software packages for the automated analysis of MS data. While data on PTMs of thousands of proteins can nowadays be readily obtained, fully deciphering the complexity and combinatorics of modification patterns even on a single protein often remains challenging. Moreover, functional investigation of PTMs on a protein of interest requires validation of the localization and the accurate quantitation of its changes across several conditions, tasks that often still require human evaluation. Software tools for large scale analyses are ...
Although not yet truly ‘comprehensive’, modern mass spectrometry-based experiments can generate quan...
Protein post-translational modifications (PTMs) are important for a variety of reasons. PTMs confer ...
Mass spectrometry (MS)–based proteomics is playing anincreasingly important role in cardiovascular r...
Mass spectrometry (MS) has become the tool of choice for the large scale identification and quantita...
Background: Proteomics is the study of the proteome, and is critical to the understanding of cellula...
The technological advances in proteomics are allowing an increasingly detailed characterization of t...
Mass spectrometry based proteomics has evolved into a powerful tool in characterising proteins and t...
The importance of post-translational modifications (PTMs) of proteins has become evident in the prot...
A post-translational modifications (PTM) is the covalent modification of a protein after its synthes...
Post-translational modifications (PTMs) can occur soon after translation or at any stage in the life...
The rate of discovery of post-translational modification (PTM) sites is increasing rapidly and is si...
Post-translational modifications (PTMs) can occur soon after translation or at any stage in the life...
Abstract only availableMass Spectrometry is an effective tool for protein identification. A typical ...
Understanding post-translational modification (PTM) of proteins and how PTMs influences cellular pro...
Abstract. Advances in tandem mass-spectrometry (MS/MS) steadily increase the rate of generation of M...
Although not yet truly ‘comprehensive’, modern mass spectrometry-based experiments can generate quan...
Protein post-translational modifications (PTMs) are important for a variety of reasons. PTMs confer ...
Mass spectrometry (MS)–based proteomics is playing anincreasingly important role in cardiovascular r...
Mass spectrometry (MS) has become the tool of choice for the large scale identification and quantita...
Background: Proteomics is the study of the proteome, and is critical to the understanding of cellula...
The technological advances in proteomics are allowing an increasingly detailed characterization of t...
Mass spectrometry based proteomics has evolved into a powerful tool in characterising proteins and t...
The importance of post-translational modifications (PTMs) of proteins has become evident in the prot...
A post-translational modifications (PTM) is the covalent modification of a protein after its synthes...
Post-translational modifications (PTMs) can occur soon after translation or at any stage in the life...
The rate of discovery of post-translational modification (PTM) sites is increasing rapidly and is si...
Post-translational modifications (PTMs) can occur soon after translation or at any stage in the life...
Abstract only availableMass Spectrometry is an effective tool for protein identification. A typical ...
Understanding post-translational modification (PTM) of proteins and how PTMs influences cellular pro...
Abstract. Advances in tandem mass-spectrometry (MS/MS) steadily increase the rate of generation of M...
Although not yet truly ‘comprehensive’, modern mass spectrometry-based experiments can generate quan...
Protein post-translational modifications (PTMs) are important for a variety of reasons. PTMs confer ...
Mass spectrometry (MS)–based proteomics is playing anincreasingly important role in cardiovascular r...