The growth in the capacity of the research community to collect and distribute data presents huge opportunities. It is already transforming old methods of scientific research and permitting the creation of new ones. However, the exploitation of these opportunities depends upon more than computing power, storage, and network connectivity. Among the promises of our growing universe of online digital data are the ability to integrate data into new forms of scholarly publishing to allow peer-examination and review of conclusions or analysis of experimental and observational data and the ability for subsequent researchers to make new analyses of the same data, including their combination with other data sets and uses that may have been unanticip...