The Correlation between Subjective and Objective Visual Function Test in Optic Neuropathy Patients

Purpose: To investigate the correlation between visual acuity and quantitative measurements of visual evoked potentials (VEP), optical coherence tomography (OCT), and visual field test (VF) in optic neuropathy patients. Methods: We evaluated 28 patients with optic neuropathy. Patients who had pale disc, visual acuity of less than 0.5 and abnormal visual field defect were included. At the first visit, we performed visual acuity and VF as subjective methods and OCT and VEP as objective methods. In the spectral domain OCT, rim volume, average and temporal quadrant retinal nerve fiber layer (RNFL) thickness were measured. And pattern VEP (N75, P100, N135 latency, and P100 amplitude) and Humphrey 24-2 visual field test (mean deviation and pattern standard deviation) were obtained. Using Spearman's correlation coefficient, the correlation between visual acuity and various techniques were assessed. Results: Visual acuity was most correlated with the mean deviation of Humphrey perimetry