BACKGROUND: Treatment with nucleotide analogs is known to be effective in inhibiting HBV replication; however, patients with chronic hepatitis B (CHB) often show a wide range of clinical responses to these drugs. Therefore, the identification of an early immunologic marker associated with the clinical outcomes in such cases is critical for the improved clinical management. In our study, we aimed to investigate whether the viral load in CHB patients affected the ratio of the number of regulatory T cells (Tregs) to the number of interleukin-17-producing helper (Th17) cells. Further, we evaluated the clinical implications of the alterations in this ratio. METHODOLOGY/PRINCIPAL FINDINGS: Nine patients seropositive for hepatitis B e antigen rece...
<div><h3>Background</h3><p>Hepatitis B virus-related liver fibrosis (HBV-LF) always progresses from ...
Disruption of peripheral blood B-cell homeostasis and variation of surface receptors occur with cert...
We aimed to investigate the influence of regulatory T cells including CD4+CD25+, CD8+CD28- and hepat...
Treatment with nucleotide analogs is known to be effective in inhibiting HBV replication; however, p...
Background and aims. CD4+ T cells play an important role in response to hepatitis B virus (HBV) infe...
Persistent infection with hepatitis B virus (HBV) is associated with host immune response. CD4+ T ce...
Abstract Background Many studies suggest that in chronic hepatitis B virus (HBV) infection regulate ...
Limited response to current hepatitis B virus (HBV) drugs is possibly due to inadequate host cytotox...
AbstractRegulatory T cells (Treg) play a key role in the impaired immune response that is typical fo...
Chronicity of hepatitis B (CHB) infection is characterized by a weak immune response to the virus. E...
Background/Aim: The effectiveness of hepatitis B virus therapy is reflected not only by the reductio...
textabstractWorldwide 400 million people suffer from chronic hepatitis B virus (HBV) infection and a...
Backround: T cell activation plays an important role in tissue injury and viral clearance during the...
BackgroundThe roles of CD4+CD25+ regulatory T cells (Treg) in chronicity of hepatitis B virus (HBV) ...
Background: Entecavir is a potent nucleoside analogue for treating chronic hepatitis B (CHB). Quanti...
<div><h3>Background</h3><p>Hepatitis B virus-related liver fibrosis (HBV-LF) always progresses from ...
Disruption of peripheral blood B-cell homeostasis and variation of surface receptors occur with cert...
We aimed to investigate the influence of regulatory T cells including CD4+CD25+, CD8+CD28- and hepat...
Treatment with nucleotide analogs is known to be effective in inhibiting HBV replication; however, p...
Background and aims. CD4+ T cells play an important role in response to hepatitis B virus (HBV) infe...
Persistent infection with hepatitis B virus (HBV) is associated with host immune response. CD4+ T ce...
Abstract Background Many studies suggest that in chronic hepatitis B virus (HBV) infection regulate ...
Limited response to current hepatitis B virus (HBV) drugs is possibly due to inadequate host cytotox...
AbstractRegulatory T cells (Treg) play a key role in the impaired immune response that is typical fo...
Chronicity of hepatitis B (CHB) infection is characterized by a weak immune response to the virus. E...
Background/Aim: The effectiveness of hepatitis B virus therapy is reflected not only by the reductio...
textabstractWorldwide 400 million people suffer from chronic hepatitis B virus (HBV) infection and a...
Backround: T cell activation plays an important role in tissue injury and viral clearance during the...
BackgroundThe roles of CD4+CD25+ regulatory T cells (Treg) in chronicity of hepatitis B virus (HBV) ...
Background: Entecavir is a potent nucleoside analogue for treating chronic hepatitis B (CHB). Quanti...
<div><h3>Background</h3><p>Hepatitis B virus-related liver fibrosis (HBV-LF) always progresses from ...
Disruption of peripheral blood B-cell homeostasis and variation of surface receptors occur with cert...
We aimed to investigate the influence of regulatory T cells including CD4+CD25+, CD8+CD28- and hepat...