Our ability to sequence genomes has provided us with near-complete lists of the proteins that compose cells, tissues, and organisms, but this is only the beginning of the process to discover the functions of cellular components. In the future, it's going to be crucial to develop computational analyses that can predict the biological functions of uncharacterised proteins. At the same time, we must not forget those fundamental experimental skills needed to confirm the predictions or send the analysts back to the drawing board to devise new ones
Successful biological analysis requires that we understand the functional interactions between key c...
How do we scale biological science to the demand of next generation biology and medicine to keep tra...
The work described in this thesis emphasizes the development of cell-based strategies with increased...
Function prediction of uncharacterized protein sequences generated by genome projects has emerged as...
With the completion of the Human Genome Project in 2001 and the subsequent explosion of organisms wi...
What does it mean for cell biologists to be working in a ‘‘post-genomic’ ’ era? This is more a media...
Genome sequencing opened the access to the information contained inside cells. Protein science will ...
Characterization of unannotated and uncharacterized protein segments is expected to lead to the disc...
BACKGROUND: With the increase in the number of genome sequencing projects, there is a concomitant...
Abstract Background While the number of newly sequenced genomes and genes is constantly increasing, ...
The availability of a rough draft of the predicted human proteome allows an evaluation of the extent...
In the recent years, a rapidly increasing amount of experimental data has been generated by high-thr...
<p>Proteins identified from the sequenced peptides were used in Ingenuity Pathway Analysis to determ...
Scientific history is made in sequencing complete genomes. Two challenges loom large: decipher the f...
Successful biological analysis requires that we understand the functional interactions between key c...
Successful biological analysis requires that we understand the functional interactions between key c...
How do we scale biological science to the demand of next generation biology and medicine to keep tra...
The work described in this thesis emphasizes the development of cell-based strategies with increased...
Function prediction of uncharacterized protein sequences generated by genome projects has emerged as...
With the completion of the Human Genome Project in 2001 and the subsequent explosion of organisms wi...
What does it mean for cell biologists to be working in a ‘‘post-genomic’ ’ era? This is more a media...
Genome sequencing opened the access to the information contained inside cells. Protein science will ...
Characterization of unannotated and uncharacterized protein segments is expected to lead to the disc...
BACKGROUND: With the increase in the number of genome sequencing projects, there is a concomitant...
Abstract Background While the number of newly sequenced genomes and genes is constantly increasing, ...
The availability of a rough draft of the predicted human proteome allows an evaluation of the extent...
In the recent years, a rapidly increasing amount of experimental data has been generated by high-thr...
<p>Proteins identified from the sequenced peptides were used in Ingenuity Pathway Analysis to determ...
Scientific history is made in sequencing complete genomes. Two challenges loom large: decipher the f...
Successful biological analysis requires that we understand the functional interactions between key c...
Successful biological analysis requires that we understand the functional interactions between key c...
How do we scale biological science to the demand of next generation biology and medicine to keep tra...
The work described in this thesis emphasizes the development of cell-based strategies with increased...