DNA methylation has been implicated in the etiopathology of various complex disorders. DNA methyltransferases are involved in maintaining and establishing new methylation patterns. The aim of the present study was to investigate the inherent genetic variations within DNA methyltransferase genes in predisposing to susceptibility to schizophrenia. We screened for polymorphisms in DNA methyltransferases, DNMT1, DNMT3A, DNMT3B and DNMT3L in 330 schizophrenia patients and 302 healthy controls for association with Schizophrenia in south Indian population. These polymorphisms were also tested for subgroup analysis with patient's gender, age of onset and family history. DNMT1 rs2114724 (genotype P = .004, allele P = 0.022) and rs2228611 (genotype P...
Epigenetic DNA methylation and Schizophrenia The evidence of Disrupted in Schizophrenia 1 (DISC...
Genetic association studies provide evidence for a substantial polygenic component to schizophrenia,...
We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from sev...
DNA methylation has been implicated in the etiopathology of various complex disorders. DNA methyltra...
Recent studies suggest that genetic and environmental factors do not account for all the schizophren...
Recent studies suggest that genetic and environmental factors do not account for all the schizophren...
Schizophrenia (SZ) is a complex disorder without a single cause but with multiple etiologies. Monozy...
Schizophrenia is a highly heritable psychiatric condition that displays a complex phenotype. A multi...
Research has shown that besides genes and environment, epigenetic factors are also playing a role in...
Emerging evidence suggests that schizophrenia (SZ) susceptibility involves variation at genetic, epi...
BACKGROUND: Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by episodic...
BACKGROUND: Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by episodic...
Recently, a significant epigenetic component in the pathology of suicide has been realized. Here we ...
Recent work has highlighted a possible role for altered epigenetic modifications, including differen...
Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea, identi...
Epigenetic DNA methylation and Schizophrenia The evidence of Disrupted in Schizophrenia 1 (DISC...
Genetic association studies provide evidence for a substantial polygenic component to schizophrenia,...
We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from sev...
DNA methylation has been implicated in the etiopathology of various complex disorders. DNA methyltra...
Recent studies suggest that genetic and environmental factors do not account for all the schizophren...
Recent studies suggest that genetic and environmental factors do not account for all the schizophren...
Schizophrenia (SZ) is a complex disorder without a single cause but with multiple etiologies. Monozy...
Schizophrenia is a highly heritable psychiatric condition that displays a complex phenotype. A multi...
Research has shown that besides genes and environment, epigenetic factors are also playing a role in...
Emerging evidence suggests that schizophrenia (SZ) susceptibility involves variation at genetic, epi...
BACKGROUND: Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by episodic...
BACKGROUND: Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by episodic...
Recently, a significant epigenetic component in the pathology of suicide has been realized. Here we ...
Recent work has highlighted a possible role for altered epigenetic modifications, including differen...
Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea, identi...
Epigenetic DNA methylation and Schizophrenia The evidence of Disrupted in Schizophrenia 1 (DISC...
Genetic association studies provide evidence for a substantial polygenic component to schizophrenia,...
We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from sev...