Pleomorphic Lobular Carcinoma of the Breast: Clinicopathological Analysis of a Distinctive and Rare Variant of Lobular Carcinoma
- Olfa El Amine
- Leila Bouhaja
- Ines Chaar
- Aida Goucha
- Ahmed El May
- Amor Gammoudi
DOIAbstract
Pleomorphic lobular carcinoma (PLC) of the breast is an uncommon variant of invasive lobular carcinoma (ILC), accounting for 0.67% of all breast carcinomas and <5% of lobular carcinoma. This lesion is usually misdiagnosed as infiltrating ductal carcinoma. It has been identified as a distinct entity from classic ILC and is reported to be associated with a more aggressive clinical behavior than classic lobular carcinoma. In this report, we aim to describe radiological and pathological characteristics of PLC and to review the therapeutic management. We present a new case of PLC occurring in a 74-year-old woman, consulting for a retro-areolar mass in the right breast, measuring 3 cm in great diameter. She underwent a mastectomy. The tumor was d...
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