Keratin (K) intermediate filaments can be divided into type I/type II proteins, which form obligate heteropolymers. Epithelial cells express type I-type II keratin pairs, and K7, K8 (type II) and K18, K19 and K20 (type I) are the primary keratins found in the single-layered intestinal epithelium. Keratins are upregulated during stress in liver, pancreas, lung, kidney and skin, however, little is known about their dynamics in the intestinal stress response. Here, keratin mRNA, protein and phosphorylation levels were studied in response to murine colonic stresses modeling human conditions, and in colorectal cancer HT29 cells. Dextran sulphate sodium (DSS)-colitis was used as a model for intestinal inflammatory stress, which elicited a strong ...
The colon mucosa is lined with crypts of circa 300 cells, forming a continuous barrier whose roles i...
Keratins (K) are intermediate filament proteins important in stress protection and mechanical suppor...
The second deadliest and third most common type of cancer is colorectal cancer (CRC). The disease me...
Keratin (K) intermediate filaments can be divided into type I/type II proteins, which form obligate ...
Intermediate filaments (IFs), a major constituent of the cellular cytoskeleton, contribute mainly to...
<div><p>Keratins (K) are important for epithelial stress protection as evidenced by keratin mutation...
Keratins (K) are important for epithelial stress protection as evidenced by keratin mutations predis...
Intermediate filament keratins (K) play a pivotal role in protein targeting and epithelialcytoprotec...
The cytoskeleton is divided into three types: microtubules, microfilaments and intermediate filament...
Keratins (K) are important for epithelial stress protection as evidenced by keratin mutations predis...
Keratin (K) intermediate filament proteins are important in stress protection and in providing mecha...
Summary: A group of keratin intermediate filament genes, the type II KRT6A-C and type I KRT16 and KR...
Keratin 8 (K8) is the main intestinal epithelial intermediate filament protein with proposed roles f...
Keratin intermediate filament proteins are major cytoskeletal components of the mammalian simple lay...
Background Keratins are intermediate filament (IF) proteins, which form part of the epithelial cytos...
The colon mucosa is lined with crypts of circa 300 cells, forming a continuous barrier whose roles i...
Keratins (K) are intermediate filament proteins important in stress protection and mechanical suppor...
The second deadliest and third most common type of cancer is colorectal cancer (CRC). The disease me...
Keratin (K) intermediate filaments can be divided into type I/type II proteins, which form obligate ...
Intermediate filaments (IFs), a major constituent of the cellular cytoskeleton, contribute mainly to...
<div><p>Keratins (K) are important for epithelial stress protection as evidenced by keratin mutation...
Keratins (K) are important for epithelial stress protection as evidenced by keratin mutations predis...
Intermediate filament keratins (K) play a pivotal role in protein targeting and epithelialcytoprotec...
The cytoskeleton is divided into three types: microtubules, microfilaments and intermediate filament...
Keratins (K) are important for epithelial stress protection as evidenced by keratin mutations predis...
Keratin (K) intermediate filament proteins are important in stress protection and in providing mecha...
Summary: A group of keratin intermediate filament genes, the type II KRT6A-C and type I KRT16 and KR...
Keratin 8 (K8) is the main intestinal epithelial intermediate filament protein with proposed roles f...
Keratin intermediate filament proteins are major cytoskeletal components of the mammalian simple lay...
Background Keratins are intermediate filament (IF) proteins, which form part of the epithelial cytos...
The colon mucosa is lined with crypts of circa 300 cells, forming a continuous barrier whose roles i...
Keratins (K) are intermediate filament proteins important in stress protection and mechanical suppor...
The second deadliest and third most common type of cancer is colorectal cancer (CRC). The disease me...