Our aim was to characterize glomerular monocytes (Mo) infiltration and to correlate them with peripheral circulating Mo subsets and severity of lupus nephritis (LN). Methods. We evaluated 48 LN biopsy samples from a referral hospital. Recognition of Mo cells was done using microscopic view and immunohistochemistry stain with CD14 and CD16. Based on the number of cells, we classified LN samples as low degree of diffuse infiltration (<5 cells) and high degree of diffuse infiltration (≥5 cells). Immunophenotyping of peripheral Mo subsets was done using flow cytometry. Results. Mean age was 34.0±11.7 years and the mean SLEDAI was 17.5±6.9. The most common SLE manifestations were proteinuria (91%) and hypocomplementemia (75%). Severe LN was foun...
Background: Systemic lupus erythematosus (SLE) is characterized by increased cardiovascular morbidit...
With the purpose of contributing to a better knowledge of the APCs functional activity in SLE, we ev...
<p>The proportion of CD14 positive cells that express CD16 cells is greater in kidneys with low numb...
Monoclonal antibody identification of infiltrating mononuclear leukocytes in lupus nephritis (LN). P...
Background The role of macrophages in the pathogenesis of lupus nephritis, in particular their di...
The detection of monocytes in human glomerulonephritis. Renal biosy specimens from 343 patients with...
Background: The roles that CD16(+) monocyte subset plays in T-cell activation and B-cell response ha...
Aim. To analyze changes in peripheral blood monocytes and their clinical significance in patients wi...
Lupus nephritis: Correlation of interstitial cells with glomerular function. Mononuclear inflammator...
We determined the association between CD14++CD16+ monocytes and subclinical infiltrates that do not ...
Characterization of mononuclear cell subsets in renal cellular interstitial infiltrates. Indirect im...
Detection of urinary macrophages expressing the CD16 (FcγRIII) molecule: A novel marker of acute inf...
Objectives Lupus nephritis (LN) is a common and severe manifestation of SLE. Memory T (TM) cells hav...
Leukocyte analysis using monoclonal antibodies in human glomerulonephritis. The leukocyte subpopulat...
Infections are frequent complications in end-stage renal failure patients undergoing hemodialysis (H...
Background: Systemic lupus erythematosus (SLE) is characterized by increased cardiovascular morbidit...
With the purpose of contributing to a better knowledge of the APCs functional activity in SLE, we ev...
<p>The proportion of CD14 positive cells that express CD16 cells is greater in kidneys with low numb...
Monoclonal antibody identification of infiltrating mononuclear leukocytes in lupus nephritis (LN). P...
Background The role of macrophages in the pathogenesis of lupus nephritis, in particular their di...
The detection of monocytes in human glomerulonephritis. Renal biosy specimens from 343 patients with...
Background: The roles that CD16(+) monocyte subset plays in T-cell activation and B-cell response ha...
Aim. To analyze changes in peripheral blood monocytes and their clinical significance in patients wi...
Lupus nephritis: Correlation of interstitial cells with glomerular function. Mononuclear inflammator...
We determined the association between CD14++CD16+ monocytes and subclinical infiltrates that do not ...
Characterization of mononuclear cell subsets in renal cellular interstitial infiltrates. Indirect im...
Detection of urinary macrophages expressing the CD16 (FcγRIII) molecule: A novel marker of acute inf...
Objectives Lupus nephritis (LN) is a common and severe manifestation of SLE. Memory T (TM) cells hav...
Leukocyte analysis using monoclonal antibodies in human glomerulonephritis. The leukocyte subpopulat...
Infections are frequent complications in end-stage renal failure patients undergoing hemodialysis (H...
Background: Systemic lupus erythematosus (SLE) is characterized by increased cardiovascular morbidit...
With the purpose of contributing to a better knowledge of the APCs functional activity in SLE, we ev...
<p>The proportion of CD14 positive cells that express CD16 cells is greater in kidneys with low numb...