The Associated with Mean Platelet Volume of the Presentation Clinical and Anjiographic of Chest Pain

Aim: Determination of risk factors in coronary heart disease has a very important place in the prevention of acute coronary syndromes besides in predicting the prognosis. Activated platelets and increased mean platelet volume play an important role in the pathogenesis of acute coronary syndromes. In our study, we investigated the relationship between MPV and chest pain, acute coronary syndromes. Material and Method: 330 patients with chest pain were included to the study. Control group consisted of 112 healthy individuals. Coronary anjiography was performed to 247 patients in in acute coronary syndrome group. The groups are compared in terms of parameters such as platelet counts, MPV, and troponin, according to its clinical and angiographic characteristics. Results: MPV leves was higher in study group than control group and there was statistically significant difference according to levels of MPV (p<0.05). There was no significant difference between groups according to levels of platelet. In clinical evaluation, there was significant difference according to MPV levels between the heart failure and other groups, and MPV levels were higher in heart failure group (p<0.05). In angiographic evaluation, there was no significant difference according to MPV and platelets levels between the groups. Discussion: In conclusion, we detected that mean platelet volumes were increased in patients presenting with acute coronary syndrome and heart failure, but we saw no difference between the subtypes of acute coronary syndrome. Based on these findings, we have concluded that larger platelet volumes may constitute a high risk for acute coronary syndrome