BACKGROUND: Sensitivity to obesity is highly variable in humans, and rats fed a high fat diet (HFD) are used as a model of this inhomogeneity. Energy expenditure components (basal metabolism, thermic effect of feeding, activity) and variations in substrate partitioning are possible factors underlying the variability. Unfortunately, in rats as in humans, results have often been inconclusive and measurements usually made after obesity onset, obscuring if metabolism was a cause or consequence. Additionally, the role of high carbohydrate diet (HCD) has seldom been studied. METHODOLOGY/FINDINGS: Rats (n=24) were fed for 3 weeks on HCD and then 3 weeks on HFD. Body composition was tracked by MRI and compared to energy expenditure components measu...
Global prevalence of obesity is increasing enormously and has more than doubled since 1980 as repor...
Background Dietary intervention studies in animal models of obesity are crucial to elucidate the mec...
The rapid rise in obesity has been linked to altered food consumption patterns. There is increasing ...
Background: Sensitivity to obesity is highly variable in humans, and rats fed a high fat diet (HFD) ...
<div><p>Background</p><p>Sensitivity to obesity is highly variable in humans, and rats fed a high fa...
Obesity-prone (OP) rodents are used as models of human obesity predisposition. The goal of the prese...
Individuals exhibit a great variation in their body weight (BW) gain response to a high fat diet. Id...
We tested the hypothesis that, for rats fed a high-fat diet (HFD), a prioritization of maintaining p...
International audienceWe previously reported that rats prone to obesity exhibit an exaggerated incre...
We previously reported that rats prone to obesity exhibit an exaggerated increase in glucose oxidati...
Animal experimentation has a long history in the study of metabolic syndrome-related disorders. Howe...
In parallel with increased prevalence of overweight people in affluent societies are individuals try...
Childhood obesity prevention is important to avoid obesity and its comorbidities into adulthood. Alt...
abstract: With the influence of the Western Diet, obesity has become a rising problem in the country...
The macronutrient component of diets is critical for metabolic control and insulin action. The aim o...
Global prevalence of obesity is increasing enormously and has more than doubled since 1980 as repor...
Background Dietary intervention studies in animal models of obesity are crucial to elucidate the mec...
The rapid rise in obesity has been linked to altered food consumption patterns. There is increasing ...
Background: Sensitivity to obesity is highly variable in humans, and rats fed a high fat diet (HFD) ...
<div><p>Background</p><p>Sensitivity to obesity is highly variable in humans, and rats fed a high fa...
Obesity-prone (OP) rodents are used as models of human obesity predisposition. The goal of the prese...
Individuals exhibit a great variation in their body weight (BW) gain response to a high fat diet. Id...
We tested the hypothesis that, for rats fed a high-fat diet (HFD), a prioritization of maintaining p...
International audienceWe previously reported that rats prone to obesity exhibit an exaggerated incre...
We previously reported that rats prone to obesity exhibit an exaggerated increase in glucose oxidati...
Animal experimentation has a long history in the study of metabolic syndrome-related disorders. Howe...
In parallel with increased prevalence of overweight people in affluent societies are individuals try...
Childhood obesity prevention is important to avoid obesity and its comorbidities into adulthood. Alt...
abstract: With the influence of the Western Diet, obesity has become a rising problem in the country...
The macronutrient component of diets is critical for metabolic control and insulin action. The aim o...
Global prevalence of obesity is increasing enormously and has more than doubled since 1980 as repor...
Background Dietary intervention studies in animal models of obesity are crucial to elucidate the mec...
The rapid rise in obesity has been linked to altered food consumption patterns. There is increasing ...