Early affective processing in patients with acute posttraumatic stress disorder: magnetoencephalographic correlates.
- Markus Burgmer
- Maimu Alissa Rehbein
- Marco Wrenger
- Judith Kandil
- Gereon Heuft
- Christian Steinberg
- Bettina Pfleiderer
- Markus Junghöfer
DOIAbstract
In chronic PTSD, a preattentive neural alarm system responds rapidly to emotional information, leading to increased prefrontal cortex (PFC) activation at early processing stages (<100 ms). Enhanced PFC responses are followed by a reduction in occipito-temporal activity during later processing stages. However, it remains unknown if this neuronal pattern is a result of a long lasting mental disorder or if it represents changes in brain function as direct consequences of severe trauma.The present study investigates early fear network activity in acutely traumatized patients with PTSD. It focuses on the question whether dysfunctions previously observed in chronic PTSD patients are already present shortly after trauma exposure. We recorded neuro...
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