The aim of this study is to investigate the actions of Chinese herbal medicine, called “Fuzheng Kang-Ai” (FZKA for short) decoction, against non-small cell lung cancer (NSCLC) and its mechanisms in vitro and in vivo. We showed that the effect of FZKA decoction significantly inhibited growth of A549 and PC9 cells. Furthermore, FZKA increased phosphorylation of AMP-activated protein kinase alpha (AMPKα) and induced protein expression of insulin-like growth factor (IGF) binding protein 1 (IGFBP1) and forkhead homeobox type O3a (FOXO3a). The specific inhibitor of AMPKα (Compound C) blocked FZKA-induced protein expression of IGFBP1 and FOXO3a. Interestingly, silencing of IGFBP1 and FOXO3a overcame the inhibitory effect of FZKA on cell growth. Mo...
Abstract Background Chinese traditional herbal medicine Fuzhengkangai (FZKA) formulation combination...
Objective: The purpose of this study was to observe the anti-cancer activity of Tonglian decoction (...
<div><p></p><p><i>Background</i>: Fangchinoline as a novel anti-tumor agent has been paid attention ...
Decoction of Chinese herbal medicine (CHM) Fuzheng Kang-Ai (FZKA for short) has been applied as adju...
Jaeumganghwa-tang (JGT, Zi-yin-jiang-huo-tang in Chinese and Jiin-koka-to in Japanese) is an orienta...
With growing evidence on the therapeutic efficacy and safety of herbal drugs, there has been a subst...
Objective: Qingzaojiufei decoction (QD) is an empirical herbal formula from traditional Chinese medi...
<div><p>Jaeumganghwa-tang (JGT, <i>Zi-yin-jiang-huo-tang</i> in Chinese and <i>Jiin-koka-to</i> in J...
Objective. Lung cancer is one of the major causes of cancer deaths worldwide, and the five-year surv...
Pancreatic cancer remains one of the leading causes of cancer-related deaths, due to aggressive grow...
Abstract Background Feifukang (FFK) is a traditional Chinese medicine composed of herbs that protect...
Chinese herbal Fu-Zheng-Qu-Xie (FZQX) prescription has been found to improve the immune function and...
AbstractObjectiveTo study the effects of a decoction of Fuzhengzengxiao formula on lung adenocarcino...
Background. Nonsmall-cell lung cancer (NSCLC) is the main type of lung cancer, whose morbidity and m...
This study was aimed to investigate the anti-tumor, anti-metastasis and immunomodulatory effects of ...
Abstract Background Chinese traditional herbal medicine Fuzhengkangai (FZKA) formulation combination...
Objective: The purpose of this study was to observe the anti-cancer activity of Tonglian decoction (...
<div><p></p><p><i>Background</i>: Fangchinoline as a novel anti-tumor agent has been paid attention ...
Decoction of Chinese herbal medicine (CHM) Fuzheng Kang-Ai (FZKA for short) has been applied as adju...
Jaeumganghwa-tang (JGT, Zi-yin-jiang-huo-tang in Chinese and Jiin-koka-to in Japanese) is an orienta...
With growing evidence on the therapeutic efficacy and safety of herbal drugs, there has been a subst...
Objective: Qingzaojiufei decoction (QD) is an empirical herbal formula from traditional Chinese medi...
<div><p>Jaeumganghwa-tang (JGT, <i>Zi-yin-jiang-huo-tang</i> in Chinese and <i>Jiin-koka-to</i> in J...
Objective. Lung cancer is one of the major causes of cancer deaths worldwide, and the five-year surv...
Pancreatic cancer remains one of the leading causes of cancer-related deaths, due to aggressive grow...
Abstract Background Feifukang (FFK) is a traditional Chinese medicine composed of herbs that protect...
Chinese herbal Fu-Zheng-Qu-Xie (FZQX) prescription has been found to improve the immune function and...
AbstractObjectiveTo study the effects of a decoction of Fuzhengzengxiao formula on lung adenocarcino...
Background. Nonsmall-cell lung cancer (NSCLC) is the main type of lung cancer, whose morbidity and m...
This study was aimed to investigate the anti-tumor, anti-metastasis and immunomodulatory effects of ...
Abstract Background Chinese traditional herbal medicine Fuzhengkangai (FZKA) formulation combination...
Objective: The purpose of this study was to observe the anti-cancer activity of Tonglian decoction (...
<div><p></p><p><i>Background</i>: Fangchinoline as a novel anti-tumor agent has been paid attention ...