It has been well known that long-term potentiation (LTP) of synaptic transmission in the lateral nucleus of the amygdala (LA) constitutes an essential cellular mechanism contributing to encoding of conditioned fear. Nitric oxide (NO), produced by activation of the postsynaptic N-methyl-D-aspartate receptors (NMDAR) in thalamic input to the LA, has been thought to promote LTP, contributing to the establishment of conditioned fear. However, it is not known whether and how NO, released from cortical input to the LA, plays the role on the plasticity induction and fear memory. Here we report that the diffusion of NO, released in response to activation of presynaptic NMDAR on cortical afferent fibers in the LA, could suppress heterosynaptically a...
AbstractFear conditioning is a valuable behavioral paradigm for studying the neural basis of emotion...
The cellular mechanisms that underlie learning and memory formation remain one of the most intriguin...
Pavlovian fear conditioning, a simple form of associative learning, is thought to involve the induct...
It has been well known that long-term potentiation (LTP) of synaptic transmission in the lateral nuc...
t has been well known that long-term potentiation (LTP) of synaptic transmission in the lateral nucl...
N-methyl-D-asparate (NMDA) receptors located within the basolateral complex of the amygdala are requ...
N-methyl-D-aspartate receptor (NMDAR)-dependent long-term depression (LTD) in the lateral nucleus of...
We examined the contribution of N-methyl-D-aspartate (NMDA) receptors (NMDARs) to the acquisition an...
The present studies investigated some of the mechanisms involved in establishing long-term fear memo...
In both invertebrate and vertebrate models of synaptic plasticity, signaling via the putative &ldquo...
Fear conditioning is a form of associative learning in which subjects come to express defense respon...
AbstractLong-term synaptic modifications in afferent inputs to the amygdala underlie fear conditioni...
Much evidence indicates that fear conditioning involves potentiation of some thalamic inputs to the ...
Stimulation of N-methyl-D-aspartic acid receptors (NMDARs) and the resulting increase of nitric oxid...
Fear and the development of conditional fear are critical for survival. However, mal-adaptations in...
AbstractFear conditioning is a valuable behavioral paradigm for studying the neural basis of emotion...
The cellular mechanisms that underlie learning and memory formation remain one of the most intriguin...
Pavlovian fear conditioning, a simple form of associative learning, is thought to involve the induct...
It has been well known that long-term potentiation (LTP) of synaptic transmission in the lateral nuc...
t has been well known that long-term potentiation (LTP) of synaptic transmission in the lateral nucl...
N-methyl-D-asparate (NMDA) receptors located within the basolateral complex of the amygdala are requ...
N-methyl-D-aspartate receptor (NMDAR)-dependent long-term depression (LTD) in the lateral nucleus of...
We examined the contribution of N-methyl-D-aspartate (NMDA) receptors (NMDARs) to the acquisition an...
The present studies investigated some of the mechanisms involved in establishing long-term fear memo...
In both invertebrate and vertebrate models of synaptic plasticity, signaling via the putative &ldquo...
Fear conditioning is a form of associative learning in which subjects come to express defense respon...
AbstractLong-term synaptic modifications in afferent inputs to the amygdala underlie fear conditioni...
Much evidence indicates that fear conditioning involves potentiation of some thalamic inputs to the ...
Stimulation of N-methyl-D-aspartic acid receptors (NMDARs) and the resulting increase of nitric oxid...
Fear and the development of conditional fear are critical for survival. However, mal-adaptations in...
AbstractFear conditioning is a valuable behavioral paradigm for studying the neural basis of emotion...
The cellular mechanisms that underlie learning and memory formation remain one of the most intriguin...
Pavlovian fear conditioning, a simple form of associative learning, is thought to involve the induct...