Effect of black soybean natto extract (Glycine soja) on reproduction system of hypercholesterolemia male mice

Objective: To analyze the effect of black soybean natto treatment on the recovery of the reproduction system in hypercholesterolemic male mice model. Methods: Thirty male mice were divided into five groups, they were normal mice (K−), a hypercholesterolemic mice model (K+), a hypercholesterolemic mice model with 200 mg/kg BW of natto extract (P1), a hypercholesterolemic mice model treated with 400 mg/kg BB of natto extract (P2), and a hypercholesterolemic mice model treated with 800 mg/kg BB of natto extract (P3). Natto extract was given orally for 30 d. Results: Black soybean natto extract influenced on reproduction system of male hypercholesterolemic mice by increasing the testosterone level and increasing the density and motility of sperm. Conclusion: Black soybean natto extract is promising as hypercholesterolemic therapy for treating the male reproduction system