Rosetting remains the dominant malaria parasite adhesion phenotype associated with severe disease and pathogenicity in Africa. The formation of rosettes, whereby a Plasmodium falciparum infected erythrocyte (IE) adheres to two or more non-IEs, is thought to facilitate the occlusion of microvascular blood vessels by adhering to host endothelial cells and other bound IEs. Current methods of determining the rosette-disrupting capabilities of antibodies/drugs have focused on static assays. As IEs in vivo are exposed to shear stresses within the microvasculature, the effect of flow conditions on rosetting requires further examination. This study establishes a new rosetting flow assay using a closed perfusion system together with inverted fluores...
Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the ...
Excessive sequestration of Plasmodium falciparum-infected erythrocytes (pRBC) and uninfected erythro...
Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the ...
<div><p>Rosetting remains the dominant malaria parasite adhesion phenotype associated with severe di...
Rosetting forces are believed to be an important contributor to the microcirculatory obstruction tha...
The spread of artemisinin-resistant parasites could lead to higher incidence of patients with malari...
<p>Antibodies to the NTSDBLα region of the PfEMP1 variant ITvar09/R29var1 were added to IT/R29 paras...
The spread of artemisinin-resistant parasites could lead to higher incidence of pati...
Noninfected erythrocytes form rosettes around those infected with trophozoites and schizonts of Plas...
Rosetting is an adhesion property of malaria parasites whereby infected erythrocytes bind to two or ...
Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the ...
The spread of artemisinin-resistant parasites could lead to higher incidence of pat...
Excessive binding of Plasmodium falciparum-infected erythrocytes to the microvascular endothelium (c...
Abstract. Red blood cells infected by mature stages of Plasmodium ovale obtained from a 56-year-old ...
Rosetting, defined as the binding of two or more uninfected red blood cells (rbc) to an infected rbc...
Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the ...
Excessive sequestration of Plasmodium falciparum-infected erythrocytes (pRBC) and uninfected erythro...
Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the ...
<div><p>Rosetting remains the dominant malaria parasite adhesion phenotype associated with severe di...
Rosetting forces are believed to be an important contributor to the microcirculatory obstruction tha...
The spread of artemisinin-resistant parasites could lead to higher incidence of patients with malari...
<p>Antibodies to the NTSDBLα region of the PfEMP1 variant ITvar09/R29var1 were added to IT/R29 paras...
The spread of artemisinin-resistant parasites could lead to higher incidence of pati...
Noninfected erythrocytes form rosettes around those infected with trophozoites and schizonts of Plas...
Rosetting is an adhesion property of malaria parasites whereby infected erythrocytes bind to two or ...
Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the ...
The spread of artemisinin-resistant parasites could lead to higher incidence of pat...
Excessive binding of Plasmodium falciparum-infected erythrocytes to the microvascular endothelium (c...
Abstract. Red blood cells infected by mature stages of Plasmodium ovale obtained from a 56-year-old ...
Rosetting, defined as the binding of two or more uninfected red blood cells (rbc) to an infected rbc...
Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the ...
Excessive sequestration of Plasmodium falciparum-infected erythrocytes (pRBC) and uninfected erythro...
Malaria parasites dramatically alter the rheological properties of infected red blood cells. In the ...