The lower immunogenicity of synthetic subunit antigens, compared to live attenuated vaccines, is being addressed with improved vaccine carriers. Recent reports indicate that the physio-chemical properties of these carriers can be altered to achieve optimal antigen presentation, endosomal escape, particle bio-distribution, and cellular trafficking. The carriers can be modified with various antigens and ligands for dendritic cells targeting. They can also be modified with adjuvants, either covalently or entrapped in the matrix, to improve cellular and humoral immune responses against the antigen. As a result, these multi-functional carrier systems are being explored for use in active immunotherapy against cancer and infectious diseases. Advan...
Conventional subunit vaccine regimes can be modified in order to stimulate strong immune responses r...
The first vaccines ever made were based on live-attenuated or inactivated pathogens, either whole ce...
Prophylactic vaccines can induce long-term, antigen-specific cellular and humoral immunity, and prov...
The lower immunogenicity of synthetic subunit antigens, compared to live attenuated vaccines, is bei...
Despite the immense public health successes of immunization over the past century, effective vaccine...
Current vaccine and immunotherapy technology faces ongoing challenges in both efficacy and practical...
By targeting dendritic cells, polymeric carriers in the nano to lower micron range constitute very i...
By targeting dendritic cells, polymeric carriers in the nano to lower micron range constitute very i...
Due to emergence of new variants of pathogenic micro-organisms the treatment and immunization of inf...
Dendritic cells (DCs) are key players in the initiation of adaptive immune responses and are current...
AbstractDespite the progress of conventional vaccines, improvements are clearly required due to conc...
Traditional vaccines, based on the administration of killed or attenuated microorganisms, have prove...
Item does not contain fulltextDendritic cells (DCs) are key players in the initiation of adaptive im...
The first vaccines ever made were based on live-attenuated or inactivated pathogens, either whole ce...
Prophylactic vaccines can induce long-term, antigen-specific cellular and humoral immunity, and prov...
Conventional subunit vaccine regimes can be modified in order to stimulate strong immune responses r...
The first vaccines ever made were based on live-attenuated or inactivated pathogens, either whole ce...
Prophylactic vaccines can induce long-term, antigen-specific cellular and humoral immunity, and prov...
The lower immunogenicity of synthetic subunit antigens, compared to live attenuated vaccines, is bei...
Despite the immense public health successes of immunization over the past century, effective vaccine...
Current vaccine and immunotherapy technology faces ongoing challenges in both efficacy and practical...
By targeting dendritic cells, polymeric carriers in the nano to lower micron range constitute very i...
By targeting dendritic cells, polymeric carriers in the nano to lower micron range constitute very i...
Due to emergence of new variants of pathogenic micro-organisms the treatment and immunization of inf...
Dendritic cells (DCs) are key players in the initiation of adaptive immune responses and are current...
AbstractDespite the progress of conventional vaccines, improvements are clearly required due to conc...
Traditional vaccines, based on the administration of killed or attenuated microorganisms, have prove...
Item does not contain fulltextDendritic cells (DCs) are key players in the initiation of adaptive im...
The first vaccines ever made were based on live-attenuated or inactivated pathogens, either whole ce...
Prophylactic vaccines can induce long-term, antigen-specific cellular and humoral immunity, and prov...
Conventional subunit vaccine regimes can be modified in order to stimulate strong immune responses r...
The first vaccines ever made were based on live-attenuated or inactivated pathogens, either whole ce...
Prophylactic vaccines can induce long-term, antigen-specific cellular and humoral immunity, and prov...