We present a method for mesoscopic, dynamic Monte Carlo simulations of pattern formation in excitable reaction-diffusion systems. Using a two-level parallelization approach, our simulations cover the whole range of the parameter space, from the noise-dominated low-particle number regime to the quasi-deterministic high-particle number limit. Three qualitatively different case studies are performed that stand exemplary for the wide variety of excitable systems. We present mesoscopic stochastic simulations of the Gray-Scott model, of a simplified model for intracellular Ca2+ oscillations and, for the first time, of the Oregonator model. We achieve simulations with up to 10(10) particles. The software and the model files are freely available an...
Spatial organization and noise play an important role in molecular systems biology. In recent years,...
Spatial stochastic reaction-diffusion simulations have become an important component of molecular mo...
Mathematical models are important tools in systems biology, since the regulatory networks in biologi...
We present a method for mesoscopic, dynamic Monte Carlo simulations of pattern formation in excitabl...
We propose a stochastic cellular automaton method to simulate chemical reactions in small systems. U...
In this paper, we address the question of the discretization of stochastic partial differential equa...
Stochastic simulations of reaction-diffusion processes are used extensively for the modeling of comp...
There is an increasing awareness of the pivotal role of noise in biochemical processes and of the ef...
With the observation that stochasticity is important in biological systems, chemical kinetics have b...
Abstract. We provide numerical simulations for nonlinear reaction-diusion systems, which arise from ...
For many biological applications, a macroscopic (deterministic) treatment of reaction-drift-diffusio...
In this dissertation, we introduce a novel accelerated-stochastic simulation method, known as the ‘p...
Traditionally, the law of mass action has been used to deterministically model chemical reactions. T...
Copyright © 2014 Daniele D’Agostino et al. This is an open access article distributed under the Crea...
A stochastic cellular automaton is developed for modeling waves in excitable media. A scale of key f...
Spatial organization and noise play an important role in molecular systems biology. In recent years,...
Spatial stochastic reaction-diffusion simulations have become an important component of molecular mo...
Mathematical models are important tools in systems biology, since the regulatory networks in biologi...
We present a method for mesoscopic, dynamic Monte Carlo simulations of pattern formation in excitabl...
We propose a stochastic cellular automaton method to simulate chemical reactions in small systems. U...
In this paper, we address the question of the discretization of stochastic partial differential equa...
Stochastic simulations of reaction-diffusion processes are used extensively for the modeling of comp...
There is an increasing awareness of the pivotal role of noise in biochemical processes and of the ef...
With the observation that stochasticity is important in biological systems, chemical kinetics have b...
Abstract. We provide numerical simulations for nonlinear reaction-diusion systems, which arise from ...
For many biological applications, a macroscopic (deterministic) treatment of reaction-drift-diffusio...
In this dissertation, we introduce a novel accelerated-stochastic simulation method, known as the ‘p...
Traditionally, the law of mass action has been used to deterministically model chemical reactions. T...
Copyright © 2014 Daniele D’Agostino et al. This is an open access article distributed under the Crea...
A stochastic cellular automaton is developed for modeling waves in excitable media. A scale of key f...
Spatial organization and noise play an important role in molecular systems biology. In recent years,...
Spatial stochastic reaction-diffusion simulations have become an important component of molecular mo...
Mathematical models are important tools in systems biology, since the regulatory networks in biologi...