Microfluctuation change of eye accommodation and efficacy of dominant eye in adolescents with ametropic amblyopia under same amount comprehensive amblyopia treatment

AIM:To explore the microfluctuation change of eye accommodation in adolescents with ametropic amblyopia under same amount comprehensive amblyopia treatment and the efficacy for dominant eye.<p>METHODS:Teenagers who took routine physical examination were chosen as the research object. Copper card method was used to identify the dominant eye and the main eye in adolescents with ametropic amblyopia which was the observation group, 63 cases with 63 eyes each. Sixty subjects with emmetropia were as the normal group. The research objects underwent mydriasis optometry, computer optometry and streak retinoscopes to determine the diopter. The patients with ametropic amblyopia were treated with same amount comprehensive amblyopia treatment, and wearing glasses. There was not any treatment for normal group. The curative effect of same amount comprehensive amblyopia treatment were tested between the observation group and the control group when treating at 1,3,6 and 12mo respectively. Microfluctuation changes when reading at the distance of 25, 33 and 50cm(5min for every distance)of the two groups were tested. Then the low frequencies(LFC)of microfluctuation change was calculated and analyzed. The whole eye aberration of the normal group and the observation group were tested with i-Trace Wave Scan Wavefront, and the corneal aberration was collected and calculated with Humphrey corneal topographer. Microfluctuation changes of the two groups were compared and the relation between the accommodation index and the wavefront aberration was analyzed.<p>RESULTS:Through statistical analysis, the LFC value of the observation group at 25, 33 and 50cm respectively was 0.086±0.022, 0.057±0.032 and 0.041±0.028D²/Hz, which was significantly higher than the LFC value of the normal group which was 0.047±0.023,0.037±0.021,0.027±0.011D²/Hz(<i>P</i><0.05). <p>CONCLUSION:Under the same amount treatment, the short-term curative effect of dominant eyes in children with ametropic amblyopia is superior to the non-dominant ones. While the differences of medium and long-term efficacy have no statistical significance. There is no difference on corneal aberration between dominant and non-dominant eyes. At near distance, the LFC of microfluctuation change was higher in amblyopia patients than that in normals