Low-Dose of Ziprasidone Induced Acute Dystonia: A Case Report

Antipsychotics medication frequently leads to different undesirable extrapyramidal side effects. Acute dystonia is one of them. It is defined as sustained abnormal postures or muscle spasms that develop within few days of starting or increasing the dose of the antipsychotic treatment or of reducing the anticholinergic medication used to treat extrapyramidal symptoms. Usually acute dystonia appears during treatment with typical antipsychotics. It is known that ziprasidone as an atypical antipsychotic drug causes less extrapyramidal side effects than typical ones do. In this report, we present a case, which developed acute dystonia after second low dose of ziprasidone (40mg/day)