The present study aimed to investigate the mode of action of nano-CaPs in vivo as a therapy for solid tumor in mice. To achieve this goal, Ehrlich Ascites Carcinoma (EAC) was transplanted into 85 Swiss male albino mice. After nine days, the mice were divided into 9 groups. Groups 1 and 2 were allocated as the EAC control. Groups 3 and 4 were injected once intratumorally (IT) by nano-calcium phosphate (nano-CaP). Groups 5 and 6 received once intraperitoneal injection (IP) of nano-CaP. Groups 7, 8, and 9 received nano-CaP (IP) weekly. Blood samples and thigh skeletal muscle were collected after three weeks from groups 1, 3, 5, and 7 and after four weeks from groups 2, 4, 6, and 8. On the other hand, group 9 received nano-CaP (IP) for four wee...
Overall cancer survival rates steadily decline each year following diagnosis and side effects of che...
The morphology, size, and surface area of nanoparticles (NPs), with the existence of functional grou...
Intracellular calcium (Ca2+) is a key signaling element that is involved in a great variety of funda...
nanoparticles EAC transplantation into 85 Swiss male albino mice. After nine days, the mice were div...
To explore an efficient gene vector in cancer gene therapy, a novel nonviral vector calcium phosphat...
In the past few decades, the successful theranostic application of nanomaterials in drug delivery sy...
Synthetic calcium phosphates (CaPs) are the most widely accepted bioceramics for the repair and reco...
Combined and targeted therapy have been extensively employed to achieve more effective elimination o...
Abstract Background Calcium phosphate (CaP) based nanoparticles are considered to be ideal drug carr...
Amorphous calcium phosphate nanoparticles (ACP NPs) exhibit excellent biocompatibility and biodegrad...
Previously, we have shown the possibility of intramucosal gastric carcinoma induction by the intraga...
Gene augmentation therapy entails replacement of the abnormal tumor suppressor genes in cancer cells...
In this study, hyaluronan (HA)-functionalized calcium phosphate nanoparticles (CaP-AHA/siRNA NPs) we...
In the past few years, we have demonstrated the efficacy of a nanoparticle system, super carbonate a...
Gene therapy is a targeted therapy which can be used in the treatment of various acquired and inheri...
Overall cancer survival rates steadily decline each year following diagnosis and side effects of che...
The morphology, size, and surface area of nanoparticles (NPs), with the existence of functional grou...
Intracellular calcium (Ca2+) is a key signaling element that is involved in a great variety of funda...
nanoparticles EAC transplantation into 85 Swiss male albino mice. After nine days, the mice were div...
To explore an efficient gene vector in cancer gene therapy, a novel nonviral vector calcium phosphat...
In the past few decades, the successful theranostic application of nanomaterials in drug delivery sy...
Synthetic calcium phosphates (CaPs) are the most widely accepted bioceramics for the repair and reco...
Combined and targeted therapy have been extensively employed to achieve more effective elimination o...
Abstract Background Calcium phosphate (CaP) based nanoparticles are considered to be ideal drug carr...
Amorphous calcium phosphate nanoparticles (ACP NPs) exhibit excellent biocompatibility and biodegrad...
Previously, we have shown the possibility of intramucosal gastric carcinoma induction by the intraga...
Gene augmentation therapy entails replacement of the abnormal tumor suppressor genes in cancer cells...
In this study, hyaluronan (HA)-functionalized calcium phosphate nanoparticles (CaP-AHA/siRNA NPs) we...
In the past few years, we have demonstrated the efficacy of a nanoparticle system, super carbonate a...
Gene therapy is a targeted therapy which can be used in the treatment of various acquired and inheri...
Overall cancer survival rates steadily decline each year following diagnosis and side effects of che...
The morphology, size, and surface area of nanoparticles (NPs), with the existence of functional grou...
Intracellular calcium (Ca2+) is a key signaling element that is involved in a great variety of funda...