INTRODUCTION:Despite recent improvements in the survival rates for nasopharyngeal carcinoma (NPC), novel treatment strategies are required to improve distant metastasis-free survival. The sodium iodine symporter (NIS) gene has been applied for in vivo imaging and cancer therapy. In this study, we examined the potential of NIS gene therapy as a therapeutic approach in NPC by performing non-invasive imaging using 125I and 131I therapy in vivo. METHODS:We constructed a lentiviral vector expressing NIS and enhanced green fluorescent protein (EGFP) under the control of the human elongation factor-1α (EF1α) promoter, and stably transfected the vector into CNE-2Z NPC cells to create CNE-2Z-NIS cells. CNE-2Z and CNE-2Z-NIS tumor xenografts were est...
We investigated the feasibility of using combination gene therapy and noninvasive nuclear imaging af...
International audienceBiotherapies involve the utilization of antibodies, genetically modified virus...
The theranostic sodium iodide symporter (NIS) gene allows detailed molecular imaging of transgene ex...
PURPOSE:The aim of this study was to design a method of radionuclide for imaging and therapy of naso...
.I were assessed over 25 days by measuring tumor volume and immunohistochemical staining of the exci...
The aim of this study was to design a method of radionuclide for imaging and therapy of nasopharynge...
Molecular imaging, defined as the visual representation, characterization and quantification of biol...
There is growing interest in the human sodium/iodide symporter (NIS) gene both as a molecular imagin...
Mesenchymal Stem Cells (MSCs) migrate specifically to tumors in vivo, and coupled with their capacit...
Human telomerase reverse transcriptase (hTERT) is highly active in most cancer cells and, thus, coul...
Aim: The purposes of this study were to establish cancer cell lines stably expressing human sodium-i...
Cloning of the sodium iodide symporter (NIS) in 1996 has provided an opportunity to use NIS as a pow...
Cloning of the sodium iodide symporter (NIS) in 1996 has provided an opportunity to use NIS as a pow...
The theranostic sodium iodide symporter (NIS) gene allows detailed molecular imaging of transgene ex...
Cloning of the sodium iodide symporter (NIS) in 1996 has provided an opportunity to use NIS as a pow...
We investigated the feasibility of using combination gene therapy and noninvasive nuclear imaging af...
International audienceBiotherapies involve the utilization of antibodies, genetically modified virus...
The theranostic sodium iodide symporter (NIS) gene allows detailed molecular imaging of transgene ex...
PURPOSE:The aim of this study was to design a method of radionuclide for imaging and therapy of naso...
.I were assessed over 25 days by measuring tumor volume and immunohistochemical staining of the exci...
The aim of this study was to design a method of radionuclide for imaging and therapy of nasopharynge...
Molecular imaging, defined as the visual representation, characterization and quantification of biol...
There is growing interest in the human sodium/iodide symporter (NIS) gene both as a molecular imagin...
Mesenchymal Stem Cells (MSCs) migrate specifically to tumors in vivo, and coupled with their capacit...
Human telomerase reverse transcriptase (hTERT) is highly active in most cancer cells and, thus, coul...
Aim: The purposes of this study were to establish cancer cell lines stably expressing human sodium-i...
Cloning of the sodium iodide symporter (NIS) in 1996 has provided an opportunity to use NIS as a pow...
Cloning of the sodium iodide symporter (NIS) in 1996 has provided an opportunity to use NIS as a pow...
The theranostic sodium iodide symporter (NIS) gene allows detailed molecular imaging of transgene ex...
Cloning of the sodium iodide symporter (NIS) in 1996 has provided an opportunity to use NIS as a pow...
We investigated the feasibility of using combination gene therapy and noninvasive nuclear imaging af...
International audienceBiotherapies involve the utilization of antibodies, genetically modified virus...
The theranostic sodium iodide symporter (NIS) gene allows detailed molecular imaging of transgene ex...