Introduction: The sabbatical leave has been recognized as a universal method to fulfill the increasing needs of academic staff to upgrade their knowledge, as well as to enhance responsiveness to their educational needs. Therefore, this study aimed to determine the existing challenges of sabbatical leave in order to be applied efficiently in each of medical universities in Iran. Methods: This qualitative applied study was conducted in 2013 in Kerman (a city in Southeast of Iran). The study data were collected through several deep interviews with 19 outstanding faculty members who were selected throughout a purposeful and systematic sampling. Topic related open questions were asked, and the data were analyzed utilizing the framework approach ...