Sleep is a vital phenomenon related to immunomodulation at the central and peripheral level. Sleep deficient in duration and/or quality is a common problem in the modern society and is considered a risk factor to develop neurodegenerative diseases. Sleep loss in rodents induces blood-brain barrier disruption and the underlying mechanism is still unknown. Several reports indicate that sleep loss induces a systemic low-grade inflammation characterized by the release of several molecules, such as cytokines, chemokines, and acute-phase proteins; all of them may promote changes in cellular components of the blood-brain barrier, particularly on brain endothelial cells. In the present review we discuss the role of inflammatory mediators that incre...
AbstractSleep loss heightens pain sensitivity, but the pathways underlying this association are not ...
The immune system is known to essentially contribute to the regulation of sleep. Whereas research in...
Good sleep is necessary for physical and mental health. For example, sleep loss impairs immune funct...
<p>Under physiological conditions adenosine modulates cerebral blood-flow and is involved in neuroph...
Immune function and sleep are two normal physiological processes to protect the living organism from...
We previously found that Mertk and its ligand Gas6, astrocytic genes involved in phagocytosis, are u...
Thermoregulation and sleep are tightly coordinated, with evidence that impairments in thermoregulati...
Good sleep is necessary for both physical and mental health; sleep and immune responses are reciproc...
Chronic sleep restriction induces blood-brain barrier disruption and increases pro-inflammatory medi...
grantor: University of TorontoThe scientific literature suggests that the sleeping-waking ...
Why does poor-quality sleep lead to atherosclerosis? In a diverse sample of over 1,600 individuals, ...
Sleep disturbance and short sleep duration are associated with inflammation and related disorders in...
Sleep is essential to human life as it regulates cognitive, metabolic, and immunological processes. ...
Abstract The damaging effects of sleep deprivation (SD) on brain parenchyma have been extensively st...
Sleep and circadian abnormalities are prevalent and burdensome manifestations of diverse neuro-immun...
AbstractSleep loss heightens pain sensitivity, but the pathways underlying this association are not ...
The immune system is known to essentially contribute to the regulation of sleep. Whereas research in...
Good sleep is necessary for physical and mental health. For example, sleep loss impairs immune funct...
<p>Under physiological conditions adenosine modulates cerebral blood-flow and is involved in neuroph...
Immune function and sleep are two normal physiological processes to protect the living organism from...
We previously found that Mertk and its ligand Gas6, astrocytic genes involved in phagocytosis, are u...
Thermoregulation and sleep are tightly coordinated, with evidence that impairments in thermoregulati...
Good sleep is necessary for both physical and mental health; sleep and immune responses are reciproc...
Chronic sleep restriction induces blood-brain barrier disruption and increases pro-inflammatory medi...
grantor: University of TorontoThe scientific literature suggests that the sleeping-waking ...
Why does poor-quality sleep lead to atherosclerosis? In a diverse sample of over 1,600 individuals, ...
Sleep disturbance and short sleep duration are associated with inflammation and related disorders in...
Sleep is essential to human life as it regulates cognitive, metabolic, and immunological processes. ...
Abstract The damaging effects of sleep deprivation (SD) on brain parenchyma have been extensively st...
Sleep and circadian abnormalities are prevalent and burdensome manifestations of diverse neuro-immun...
AbstractSleep loss heightens pain sensitivity, but the pathways underlying this association are not ...
The immune system is known to essentially contribute to the regulation of sleep. Whereas research in...
Good sleep is necessary for physical and mental health. For example, sleep loss impairs immune funct...