Angiotensin-converting enzyme gene (ACE) insertion/deletion (I/D) polymorphism have long been linked to sporadic Alzheimer disease (SAD), but the established data remained controversial. To clarify this inconsistency, a comprehensive meta-analysis was conducted. Through searching of Pubmed, Embase, Alzgene, China National Knowledge Infrastructure (CNKI) and manually searching relevant references, 53 independent studies from 48 articles were included, involving a total of 8153 cases and 14932 controls. The strength of association was assessed by using odds ratios (ORs) with 95% confidence intervals (CIs). Further stratified analyses and heterogeneity analyses were tested, as was publication bias. Overall, significant associations were reveal...
Background: Many studies have investigated the association between the angiotensin-converting enzyme...
Item does not contain fulltextOBJECTIVES: To examine the association between the angiotensin-convert...
A key pathological feature of late-onset Alzheimer's disease (LOAD) is the abnormal extracellular ac...
Angiotensin-converting enzyme gene (ACE) insertion/deletion (I/D) polymorphism have long been linked...
Epidemiological and pathogenetic evidences suggest a strong association between vascular risk factor...
Apolipoprotein E epsilon4 (APOE*4) is the only fully established susceptibility allele for Alzheimer...
Background: Angiotensin-converting enzyme has been reported to show altered activity in patients wit...
Several studies have shown that a common insertion (I)/deletion (D) polymorphism of angiotensin-conv...
Several lines of evidence support for a role of angiotensin converting enzyme (ACE) in Alzheimer dis...
AbstractIntroductionAlzheimer’s disease (AD) is a progressive, neurodegenerative disease. Many studi...
Abstract Background The angiotensin-converting enzyme gene (ACE) insertion/deletion (I/D or indel) p...
Numerous genes have been implicated in Alzheimer's disease (AD), but, with the exception of a demons...
Introduction: Alzheimer’s disease (AD) is a progressive, neurodegenerative disease. Many studies pro...
A recent study suggested that the insertion (I) allele in intron 16 of the angiotensin converting en...
BACKGROUND: Many studies have investigated the association between the angiotensin-converting enzyme...
Background: Many studies have investigated the association between the angiotensin-converting enzyme...
Item does not contain fulltextOBJECTIVES: To examine the association between the angiotensin-convert...
A key pathological feature of late-onset Alzheimer's disease (LOAD) is the abnormal extracellular ac...
Angiotensin-converting enzyme gene (ACE) insertion/deletion (I/D) polymorphism have long been linked...
Epidemiological and pathogenetic evidences suggest a strong association between vascular risk factor...
Apolipoprotein E epsilon4 (APOE*4) is the only fully established susceptibility allele for Alzheimer...
Background: Angiotensin-converting enzyme has been reported to show altered activity in patients wit...
Several studies have shown that a common insertion (I)/deletion (D) polymorphism of angiotensin-conv...
Several lines of evidence support for a role of angiotensin converting enzyme (ACE) in Alzheimer dis...
AbstractIntroductionAlzheimer’s disease (AD) is a progressive, neurodegenerative disease. Many studi...
Abstract Background The angiotensin-converting enzyme gene (ACE) insertion/deletion (I/D or indel) p...
Numerous genes have been implicated in Alzheimer's disease (AD), but, with the exception of a demons...
Introduction: Alzheimer’s disease (AD) is a progressive, neurodegenerative disease. Many studies pro...
A recent study suggested that the insertion (I) allele in intron 16 of the angiotensin converting en...
BACKGROUND: Many studies have investigated the association between the angiotensin-converting enzyme...
Background: Many studies have investigated the association between the angiotensin-converting enzyme...
Item does not contain fulltextOBJECTIVES: To examine the association between the angiotensin-convert...
A key pathological feature of late-onset Alzheimer's disease (LOAD) is the abnormal extracellular ac...