A meta-analysis of site-specific effects of cathodal transcranial direct current stimulation on sensory perception and pain.

Bita Vaseghi
Maryam Zoghi
Shapour Jaberzadeh

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DOI

10.1371/journal.pone.0123873

Publisher

Public Library of Science (PLoS)

Journal

issn:1932-6203

Abstract

The primary aim of our meta-analysis was to evaluate the effects of cathodal transcranial direct current stimulation (c-tDCS) on sensory and pain thresholds (STh and PTh) in healthy individuals and pain level (PL) in patients with chronic pain. Electronic databases were searched for c-tDCS studies. Methodological quality was evaluated using the PEDro and Downs and Black (D&B) assessment tools. C-tDCS of the primary motor cortex (S1) increases both STh (P<0.001, effect size of 26.84%) and PTh (P<0.001, effect size of 11.62%). In addition, c-tDCS over M1 led to STh increase (P<0.005, effect size of 30.44%). Likewise, PL decreased significantly in the patient group following application of c-tDCS. The small number of studies precluded subgroup...

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A meta-analysis of site-specific effects of cathodal transcranial direct current stimulation on sensory perception and pain.

Abstract

Extracted data

A meta-analysis of site-specific effects of cathodal transcranial direct current stimulation on sensory perception and pain.

Abstract

Extracted data

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