HPV Negative Seborrheic Keratosis of Genital Area

Seborrheic keratoses (SK) are most common tumors and they are most common on the trunk. The lessions are found in varying color brown to black and forms; papules, plaques, nodules. The origin of SK is unknown. Although they often have the same gross and microscopic patterns with common warts, human papilloma virus (HPV) particles are usually not present. Seborrheic keratoses rarely occurs in the genital area and is often neglected in differential diagnosis of polypoidal lesions like condylomas. Because os a rare condition here a case of 41 year-old, male patient with seborrheic keratoses in the genital area was presented. Human papilloma virus DNA was not detected in the lesion by hybrid capture 2 assay. Seborrheic keratoses should be considered in the differential diagnosis of condylomas and the diagnosis should be confirmed by dermoscopy and histopathology. HPV screening in these lesions will help to clarify the pathogenic contributing role of HPV