The association of lung cancer with changes in microRNAs in plasma shown in multiple studies suggests a utility for circulating microRNA biomarkers in non-invasive detection of the disease. We examined if presence of lung cancer is reflected in whole blood microRNA expression as well, possibly because of a systemic response. Locked nucleic acid microarrays were used to quantify the global expression of microRNAs in whole blood of 22 patients with lung adenocarcinoma and 23 controls, ten of whom had a radiographically detected non-cancerous lung nodule and the other 13 were at high risk for developing lung cancer because of a smoking history of >20 pack-years. Cases and controls differed significantly for age with a mean difference of 10.7 y...
Lung cancer is a leading cause of cancer death and late diagnosis is one of the most important reaso...
Background: Micro(mi)RNAs, potent gene expression regulators associated with tumorigenesis, are stab...
<div><p>Lung cancer is the major human malignancy, accounting for 30% of all cancer-related deaths w...
<div><p>The association of lung cancer with changes in microRNAs in plasma shown in multiple studies...
Lung cancer (LC) is currently the world’s leading cause of cancer-related mortality with overall mor...
Detection of lung cancer at an early stage by sensitive screening tests could be an important strate...
Detection of lung cancer at an early stage by sensitive screening tests could be an important strate...
Lung cancer is the most common cause of cancer deaths worldwide. MicroRNAs (miRNAs) are short, non-c...
Lung cancer is one of major cancers, and survival of lung cancer patients is dictated by the timely ...
Lung cancer is the most common cause of cancer deaths worldwide and numerous ongoing research effort...
BackgroundThe analysis of circulating tumor nucleic acids (DNAs and RNAs) in the blood seems to be a...
Lung cancer is the major human malignancy, accounting for 30% of all cancer-related deaths worldwide...
PurposeTo identify potential molecular targets for lung cancer intervention and diagnosis, we analyz...
Background: Despite extensive endeavors to establish cell-free circulating biomarkers for lung cance...
Lung cancer is the major human malignancy, accounting for 30 % of all cancer-related deaths worldwid...
Lung cancer is a leading cause of cancer death and late diagnosis is one of the most important reaso...
Background: Micro(mi)RNAs, potent gene expression regulators associated with tumorigenesis, are stab...
<div><p>Lung cancer is the major human malignancy, accounting for 30% of all cancer-related deaths w...
<div><p>The association of lung cancer with changes in microRNAs in plasma shown in multiple studies...
Lung cancer (LC) is currently the world’s leading cause of cancer-related mortality with overall mor...
Detection of lung cancer at an early stage by sensitive screening tests could be an important strate...
Detection of lung cancer at an early stage by sensitive screening tests could be an important strate...
Lung cancer is the most common cause of cancer deaths worldwide. MicroRNAs (miRNAs) are short, non-c...
Lung cancer is one of major cancers, and survival of lung cancer patients is dictated by the timely ...
Lung cancer is the most common cause of cancer deaths worldwide and numerous ongoing research effort...
BackgroundThe analysis of circulating tumor nucleic acids (DNAs and RNAs) in the blood seems to be a...
Lung cancer is the major human malignancy, accounting for 30% of all cancer-related deaths worldwide...
PurposeTo identify potential molecular targets for lung cancer intervention and diagnosis, we analyz...
Background: Despite extensive endeavors to establish cell-free circulating biomarkers for lung cance...
Lung cancer is the major human malignancy, accounting for 30 % of all cancer-related deaths worldwid...
Lung cancer is a leading cause of cancer death and late diagnosis is one of the most important reaso...
Background: Micro(mi)RNAs, potent gene expression regulators associated with tumorigenesis, are stab...
<div><p>Lung cancer is the major human malignancy, accounting for 30% of all cancer-related deaths w...