Change of ocular surface in patients with proliferative diabetic retinopathy after phacoemulsification with intraocular lens implantation and vitrectomy using Resight non-contact wide-angle lens

AIM: To evaluate the difference of ocular surface between Resight non-contact wide-angle lens and conventional corneal contact lens in the patients with proliferative diabetic retinopathy(PDR)after phacoemulsification combined with intraocular lens(IOL)implantation and vitrectomy. <p>METHODS: A retrospective cases-controlled study was designed.Ninety-six patients(96 eyes)with PDR and cataract were included in this study from January 2014 to December 2014 in Traditional Chinese Medical Hospital of Xinjiang Uygur Autonomous Region.The 48 cases(48 eyes)in experiment group were treated with Resight non-contact wide-angle lens,the 48 cases(48 eyes)in control group with conventional corneal contact lens. Corneal thickness(CT), Schirmer's test(SⅠt),breaking-up time(BUT)and corneal fluorescein staining(CFS)were taken before operations and at 1d,1wk and 1mo after operations. <p>RESULTS: All indicators of the two groups had no significant differences preoperatively. Significant differences were found on CT value between the experiment group and control group as well as among 4 time points(<i>F_time</i>=748.355,<i>P</i>=0.000; <i>F_group</i>=27.196,<i>P</i>=0.000). The CT value of the control group increased obviously after surgeries, the differences were significant compared with preoperative(<i>P</i><0.05). The SⅠt of the two groups among the 4 points were significantly different(<i>F_time</i>=571.094,<i>P</i>=0.000). The SⅠt of the two groups at 1d and 1wk were significantly different compared with those preoperative(<i>P</i><0.05). The SⅠt of the two groups at 1mo postoperatively recovered to the same level as before surgeries. The BUT value between the two groups as well as among 4 time points were significantly different(<i>F_time</i>=843.122,<i>P</i>=0.000; <i>F_group</i>=24.664,<i>P</i>=0.000). The BUT decreased after surgeries and the differences were significant, compared with those before surgeries(<i>P</i><0.05). The CFS value between the two groups as well as among 4 time points were significantly different(<i>F_time</i>=312.093,<i>P</i>=0.000; <i>F_group</i>=16.232,<i>P</i>=0.000). The CFS value after surgeries was higher than those before surgeries and the differences were significant(<i>P</i><0.05).<p>CONCLUSION: Resight non-contact wide-angle lens has little influence on the ocular surface in the patients with PDR after phacoemulsification combined with IOL implantation and vitrectomy