Evaluation of Subclinical Inflammation with Neutrophil Lymphocyte Ratio In Heavy Metal Exposure

Aim: Neutrophil lymphocyte ratio (NLR) is being used frequently as a marker of subclinical inflammation. The objective of this study is to investigate the association between NLR levels and heavy metal levels in workers with lead exposure. Material and Method: Demographic and laboratory data of 1820 individuals with lead exposure were evaluated retrospectively. C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and complete blood count (CBC) were evaluated as inflammatory markers. Participants were categorized into 3 groups according to blood lead levels as < 10 %u03BCg/dL (Group 1), 10-30 %u03BCg/dL (Group 2), and > 30 %u03BCg/dL(Group 3). The association between NLR and lead was evaluated by inter-group and correlation analysis. Results: Median NLR values of Group 1, Group 2 and Group 3 were 1.45 (0.41-1.97), 1.92 (1.19-1.42), and 1,96 (1.19-7.55) respectively (