mRNA for biomarkers of kidney injury extracted from urinary exosomes may reflect or predict levels of the corresponding protein after transplantation and clinical outcomes.Urinary exosomes were isolated from patients following renal transplantation, from healthy controls, and patients with CKD. Expression of exosomal mRNA for the injury biomarkers neutrophil gelatinase-associated lipocalin (NGAL), interleukin-18 (IL-18), kidney injury molecule-1 (KIM-1), and cystatin C was compared with the concentrations of corresponding urinary proteins, 18S RNA and serum creatinine.All biomarker protein concentrations increased after transplantation, and urinary NGAL and IL-18 at 24 and 168 h correlated with the day 7 creatinine reduction ratio (CRR). Ex...
Contains fulltext : 174177.pdf (Publisher’s version ) (Open Access)Urine represent...
Kidney transplantation is the preferred renal replacement therapy available. Yet, long-term transpla...
The diagnosis of acute kidney injury (AKI) traditionally depends on the serum creatinine (Scr) and u...
BACKGROUND: mRNA for biomarkers of kidney injury extracted from urinary exosomes may reflect or pred...
BackgroundUrine exosomes are small vesicles exocytosed into the urine by all renal epithelial cell t...
In clinical practice, there is a lack of markers for the non-invasive diagnosis and follow-up of kid...
Background. Chronic transplant dysfunction is characterized by renal function decline and proteinuri...
BackgroundAcute rejection is hazardous to graft survival in kidney transplant recipients (KTRs). We ...
BACKGROUND: Acute renal dysfunction still constitutes a highly significant obstacle to renal transpl...
Purpose: Kidney injury molecule (KIM)-1, a transmembrane-tubular protein, is excreted in the urine w...
BACKGROUND:Acute rejection is hazardous to graft survival in kidney transplant recipients (KTRs). We...
Urinary exosomes containing apical membrane and intracellular fluid are normally secreted into the u...
Extracellular vesicles (EVs) are nanoparticles that transmit molecules from releasing cells to targe...
BACKGROUND: The measurement of urinary biomarkers during ex-vivo normothermic kidney perfusion (EVKP...
Urinary exosomes are excreted from all nephron segments and constitute a rich source of intracellula...
Contains fulltext : 174177.pdf (Publisher’s version ) (Open Access)Urine represent...
Kidney transplantation is the preferred renal replacement therapy available. Yet, long-term transpla...
The diagnosis of acute kidney injury (AKI) traditionally depends on the serum creatinine (Scr) and u...
BACKGROUND: mRNA for biomarkers of kidney injury extracted from urinary exosomes may reflect or pred...
BackgroundUrine exosomes are small vesicles exocytosed into the urine by all renal epithelial cell t...
In clinical practice, there is a lack of markers for the non-invasive diagnosis and follow-up of kid...
Background. Chronic transplant dysfunction is characterized by renal function decline and proteinuri...
BackgroundAcute rejection is hazardous to graft survival in kidney transplant recipients (KTRs). We ...
BACKGROUND: Acute renal dysfunction still constitutes a highly significant obstacle to renal transpl...
Purpose: Kidney injury molecule (KIM)-1, a transmembrane-tubular protein, is excreted in the urine w...
BACKGROUND:Acute rejection is hazardous to graft survival in kidney transplant recipients (KTRs). We...
Urinary exosomes containing apical membrane and intracellular fluid are normally secreted into the u...
Extracellular vesicles (EVs) are nanoparticles that transmit molecules from releasing cells to targe...
BACKGROUND: The measurement of urinary biomarkers during ex-vivo normothermic kidney perfusion (EVKP...
Urinary exosomes are excreted from all nephron segments and constitute a rich source of intracellula...
Contains fulltext : 174177.pdf (Publisher’s version ) (Open Access)Urine represent...
Kidney transplantation is the preferred renal replacement therapy available. Yet, long-term transpla...
The diagnosis of acute kidney injury (AKI) traditionally depends on the serum creatinine (Scr) and u...