Although plasma corticosterone is considered the main glucocorticoid involved in regulation of stress responses in rodents, the presence of plasma cortisol and whether its level can be used as an indicator for rodent activation of stress remain to be determined. In this study, effects of estrous cycle stage, circadian rhythm, and acute and chronic (repeated or unpredictable) stressors of various severities on dynamics and correlation of serum cortisol and corticosterone were examined in mice. A strong (r = 0.6-0.85) correlation between serum cortisol and corticosterone was observed throughout the estrous cycle, all day long, and during acute or repeated restraints, chronic unpredictable stress and acute forced swimming or heat stress. Both ...
<p>Values without a common letter differ (P < 0.05) within cortisol or corticosterone groups.</p
The effects of brief stressor exposure on hypothalamic-pituitary-adrenal (HPA) functioning was asses...
Serum corticosterone levels of Dom and Sub mice sacrificed immediately following 45 minutes of restr...
<p>Values without a common letter differ (P < 0.05) within cortisol or corticosterone groups.</p
<p>Values without a common letter differ (P < 0.05) within cortisol or corticosterone groups.</p
<p>Female <b>(A)</b> and male <b>(B)</b> wt, Epac1<sup>-/-</sup>, Epac2<sup>-/-</sup> and Epac1/2<su...
Plasma corticosterone levels were measured in the pregnant and non-pregnant mouse after acute and ch...
<p>Mean (± SEM) plasma corticosterone concentrations (µg/dl) among male (upper) and female (lower) m...
A detailed protocol is described to induce chronic stress in BALB/c mice, which affects the hypothal...
The hypothalamic-pituitary-adrenal (HPA) axis is important in regulating energy metabolism and in me...
<p>Diurnal plasma corticosterone (A) and melatonin (B) levels (means ± SEM) in mice under continuous...
The present study was designed to examine serum Corticosterone levels following exposure to stressor...
<p>Histograms represent plasma corticosterone concentrations (mean + SEM) in 8 week-old mice in the ...
<p>Assessment of plasma corticosterone levels of male (<b>A</b>) and female (<b>B</b>) control (con)...
<p><b>A</b>: On days 3, 6, 9, 12, 15, 18, and 21, CRS and CUMS did not inhibit mice body weight gain...
<p>Values without a common letter differ (P < 0.05) within cortisol or corticosterone groups.</p
The effects of brief stressor exposure on hypothalamic-pituitary-adrenal (HPA) functioning was asses...
Serum corticosterone levels of Dom and Sub mice sacrificed immediately following 45 minutes of restr...
<p>Values without a common letter differ (P < 0.05) within cortisol or corticosterone groups.</p
<p>Values without a common letter differ (P < 0.05) within cortisol or corticosterone groups.</p
<p>Female <b>(A)</b> and male <b>(B)</b> wt, Epac1<sup>-/-</sup>, Epac2<sup>-/-</sup> and Epac1/2<su...
Plasma corticosterone levels were measured in the pregnant and non-pregnant mouse after acute and ch...
<p>Mean (± SEM) plasma corticosterone concentrations (µg/dl) among male (upper) and female (lower) m...
A detailed protocol is described to induce chronic stress in BALB/c mice, which affects the hypothal...
The hypothalamic-pituitary-adrenal (HPA) axis is important in regulating energy metabolism and in me...
<p>Diurnal plasma corticosterone (A) and melatonin (B) levels (means ± SEM) in mice under continuous...
The present study was designed to examine serum Corticosterone levels following exposure to stressor...
<p>Histograms represent plasma corticosterone concentrations (mean + SEM) in 8 week-old mice in the ...
<p>Assessment of plasma corticosterone levels of male (<b>A</b>) and female (<b>B</b>) control (con)...
<p><b>A</b>: On days 3, 6, 9, 12, 15, 18, and 21, CRS and CUMS did not inhibit mice body weight gain...
<p>Values without a common letter differ (P < 0.05) within cortisol or corticosterone groups.</p
The effects of brief stressor exposure on hypothalamic-pituitary-adrenal (HPA) functioning was asses...
Serum corticosterone levels of Dom and Sub mice sacrificed immediately following 45 minutes of restr...