Sporadic Creutzfeldt-Jakob disease (sCJD), the most frequent human prion disorder, is characterized by remarkable phenotypic variability, which is influenced by the conformation of the pathologic prion protein and the methionine/valine polymorphic codon 129 of the prion protein gene. While the etiology of sCJD remains unknown, it has been hypothesized that environmental exposure to prions might occur through conjunctival/mucosal contact, oral ingestion, inhalation, or simultaneous involvement of the olfactory and enteric systems. We studied 21 subjects with definite sCJD to assess neuropathological involvement of the dorsal motor nucleus of the vagus and other medullary nuclei and to evaluate possible associations with codon 129 genotype an...
ABSTRACT Sporadic Creutzfeldt-Jakob disease (sCJD) cases are currently classified according to the m...
<div><h3>Background</h3><p>Prion diseases are a group of invariably fatal neurodegenerative disorder...
subtypes or a spectrum of disease? Although the condition we now call sporadic Creutzfeldt–Jakob dis...
Sporadic Creutzfeldt-Jakob disease (sCJD), the most frequent human prion disorder, is characterized ...
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are mammalian neurodegenerative...
In 2007, we reported a patient with an atypical form of Creutzfeldt-Jakob disease (CJD), heterozygou...
International audienceSporadic Creutzfeldt-Jakob disease (sCJD) cases are classified according to th...
The methionine (M)-valine (V) polymorphic codon 129 of the prion protein gene (PRNP) plays a central...
Sporadic Creutzfeldt-Jakob disease (CJD), the most common human prion disease, is generally regarded...
Background: Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder in humans...
Human prion diseases have inherited, sporadic, and acquired etiologies. The appearance of the novel ...
A characteristic feature of Creutzfeldt-jakob disease (CJD) is the accumulation in the brain of the ...
As an experimental model of acquired Creutzfeldt-Jakob disease (CJD), we performed transmission stud...
BACKGROUND: Olfactory cortexes and the olfactory tracts are involved in sporadic Creutzfeldt–Jakob d...
Human prion diseases have inherited, sporadic, and acquired etiologies. The appearance of the novel ...
ABSTRACT Sporadic Creutzfeldt-Jakob disease (sCJD) cases are currently classified according to the m...
<div><h3>Background</h3><p>Prion diseases are a group of invariably fatal neurodegenerative disorder...
subtypes or a spectrum of disease? Although the condition we now call sporadic Creutzfeldt–Jakob dis...
Sporadic Creutzfeldt-Jakob disease (sCJD), the most frequent human prion disorder, is characterized ...
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are mammalian neurodegenerative...
In 2007, we reported a patient with an atypical form of Creutzfeldt-Jakob disease (CJD), heterozygou...
International audienceSporadic Creutzfeldt-Jakob disease (sCJD) cases are classified according to th...
The methionine (M)-valine (V) polymorphic codon 129 of the prion protein gene (PRNP) plays a central...
Sporadic Creutzfeldt-Jakob disease (CJD), the most common human prion disease, is generally regarded...
Background: Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder in humans...
Human prion diseases have inherited, sporadic, and acquired etiologies. The appearance of the novel ...
A characteristic feature of Creutzfeldt-jakob disease (CJD) is the accumulation in the brain of the ...
As an experimental model of acquired Creutzfeldt-Jakob disease (CJD), we performed transmission stud...
BACKGROUND: Olfactory cortexes and the olfactory tracts are involved in sporadic Creutzfeldt–Jakob d...
Human prion diseases have inherited, sporadic, and acquired etiologies. The appearance of the novel ...
ABSTRACT Sporadic Creutzfeldt-Jakob disease (sCJD) cases are currently classified according to the m...
<div><h3>Background</h3><p>Prion diseases are a group of invariably fatal neurodegenerative disorder...
subtypes or a spectrum of disease? Although the condition we now call sporadic Creutzfeldt–Jakob dis...