Chemerin is a protein ligand for the G protein-coupled receptor CMKLR1 and also binds to two atypical heptahelical receptors, CCRL2 and GPR1. Chemerin is a leukocyte attractant, adipokine, and antimicrobial protein. Although chemerin was initially identified as a highly expressed gene in healthy skin keratinocytes that was downregulated during psoriasis, the regulation of chemerin and its receptors in the skin by specific cytokines and microbial factors remains unexplored. Here we show that chemerin, CMKLR1, CCRL2 and GPR1 are expressed in human and mouse epidermis, suggesting that this tissue may be both a source and target for chemerin mediated effects. In human skin cultures, chemerin is significantly downregulated by IL-17 and IL-22, ke...
Chemerin is a chemotactic protein that induces migration of several immune cells including macrophag...
Chemerin is an adipokine secreted by adipocytes and associated with obesity, insulin resistance and ...
Chemerin, a chemoattractant protein and adipokine, has been identified as the endogenous ligand for ...
Chemerin is a protein ligand for the G protein-coupled receptor CMKLR1 and also binds to two atypica...
Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share simi...
Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share simi...
Psoriasis is a type I interferon-driven T cell-mediated disease characterized by the recruitment of ...
Psoriasis is a type I interferon-driven T cell-mediated disease characterized by the recruitment of ...
Psoriasis is a type I interferon-driven T cell – mediated disease characterized by the recruitment ...
Chemerin is recently discovered ligand for a chemokine receptor like-1 (CMKLR1) expressed primarily ...
<p>Chemerin mRNA expression (A), chemerin protein expression in tissue lysates (B), and chemerin rec...
Chemerin is a multifunctional protein acting mainly through the G protein-coupled receptor ChemR23/C...
Chemerin is a novel chemoattractant recognized by chemokine-like receptor 1 (CMKLR1), a serpentine r...
<p>Chemerin mRNA expression (A), chemerin protein expression in tissue lysates (B), chemerin recepto...
Inflammation is a normal physiological response to invading pathogens or tissue injury. However, if ...
Chemerin is a chemotactic protein that induces migration of several immune cells including macrophag...
Chemerin is an adipokine secreted by adipocytes and associated with obesity, insulin resistance and ...
Chemerin, a chemoattractant protein and adipokine, has been identified as the endogenous ligand for ...
Chemerin is a protein ligand for the G protein-coupled receptor CMKLR1 and also binds to two atypica...
Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share simi...
Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share simi...
Psoriasis is a type I interferon-driven T cell-mediated disease characterized by the recruitment of ...
Psoriasis is a type I interferon-driven T cell-mediated disease characterized by the recruitment of ...
Psoriasis is a type I interferon-driven T cell – mediated disease characterized by the recruitment ...
Chemerin is recently discovered ligand for a chemokine receptor like-1 (CMKLR1) expressed primarily ...
<p>Chemerin mRNA expression (A), chemerin protein expression in tissue lysates (B), and chemerin rec...
Chemerin is a multifunctional protein acting mainly through the G protein-coupled receptor ChemR23/C...
Chemerin is a novel chemoattractant recognized by chemokine-like receptor 1 (CMKLR1), a serpentine r...
<p>Chemerin mRNA expression (A), chemerin protein expression in tissue lysates (B), chemerin recepto...
Inflammation is a normal physiological response to invading pathogens or tissue injury. However, if ...
Chemerin is a chemotactic protein that induces migration of several immune cells including macrophag...
Chemerin is an adipokine secreted by adipocytes and associated with obesity, insulin resistance and ...
Chemerin, a chemoattractant protein and adipokine, has been identified as the endogenous ligand for ...