An investigation of the impact of bacterial diversity, pathogenic determinants and biofilms on chronic wounds

The researcher investigated the abundance and diversity of bacteria in chronic wounds. Chronic wounds are a significant public health burden and associated with complex polymicrobial communities. Bacterial colonization has been hypothesized to be one of the main underlying causes of chronic wounds and leads to detrimental effects on wound healing. Next-generation sequencing technologies were utilized to identify possible bacterial biomarkers to predict wound healing trajectory. Overall, bacterial bioburden and their molecular characteristics were found to be associated with and predictive of poor wound healing outcomes. This research has been presented at conferences and in publications