Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets
- Ylipaasto, Petri
- Kutlu, Burak
- Rasilainen, Suvi
- Rasschaert, Joanne
- Salmela, K.
- Teerijoki, Heli
- Korsgren, Olle
- Lahesmaa, Riitta
- Hovi, T
- Eizirik, Decio L.
- Otonkoski, Timo
- Roivainen, Merja
Publication date
January 2005
DOI Publisher
Springer Science and Business Media LLCAbstract
It is thought that enterovirus infections initiate or facilitate the pathogenetic processes leading to type 1 diabetes. Exposure of cultured human islets to cytolytic enterovirus strains kills beta cells after a protracted period, suggesting a role for secondary virus-induced factors such as cytokines.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Add to ORKG