Two series of analogues of the marine pyrroloiminoquinone alkaloids tsitsikammamine have been synthesized on the basis of a Michael addition between 2'-amino-1-(4-methoxyphenyl)-ethanol and two indolediones. All the compounds were evaluated in vitro for antiproliferative activity against distinct cancer cell lines.Journal Articleinfo:eu-repo/semantics/publishe
Pyrroloiminoquinones are a group of cytotoxic alkaloids most commonly isolated from marine sponges. ...
Marine organisms have proven to be a promising source of new compounds with activity against tumor c...
Synthesis of 10 pyrroloiminoquinone derivatives is presented. The strategy is based around the elabo...
Two series of analogues of the marine pyrroloiminoquinone alkaloids tsitsikammamine have been synthe...
International audienceIndoleamine 2,3-dioxygenase (IDO1) and tryptophane 2,3-dioxygenase (TDO) are t...
Les alcaloïdes marins Wakayine et Tsitsikammamine appartiennent à la famille des 1,3,4,5-tétrahydrop...
Two strategies have been investigated for the synthesis of the marine alkaloid wakayin resulting in ...
Tsitsikammamines are marine alkaloids whose structure is based on the pyrroloiminoquinone scaffold. ...
The tetrahydroazepinone pharmacophore is a component of many interesting compounds, including severa...
Tsitsikammamines are marine alkaloids whose structure is based on the pyrroloiminoquinone scaffold. ...
A series of pyrrolic analogs and two series of regioisomeric pyrazolic analogs of the marine alkaloi...
The marine alkaloids Wakayin and Tsitsikammamine belong to the 1,3,4,5-tetrahydropyrrolo [4,3,2-de] ...
A series of pyrrolic analogs and two series of regioisomeric pyrazolic analogs of the marine alkaloi...
Indoleamine 2,3-dioxygenase (IDO1) and tryptophane 2,3-dioxygenase (TDO) are two heme-containing enz...
International audienceThis work describes the synthesis and biological evaluation of a new heterocyc...
Pyrroloiminoquinones are a group of cytotoxic alkaloids most commonly isolated from marine sponges. ...
Marine organisms have proven to be a promising source of new compounds with activity against tumor c...
Synthesis of 10 pyrroloiminoquinone derivatives is presented. The strategy is based around the elabo...
Two series of analogues of the marine pyrroloiminoquinone alkaloids tsitsikammamine have been synthe...
International audienceIndoleamine 2,3-dioxygenase (IDO1) and tryptophane 2,3-dioxygenase (TDO) are t...
Les alcaloïdes marins Wakayine et Tsitsikammamine appartiennent à la famille des 1,3,4,5-tétrahydrop...
Two strategies have been investigated for the synthesis of the marine alkaloid wakayin resulting in ...
Tsitsikammamines are marine alkaloids whose structure is based on the pyrroloiminoquinone scaffold. ...
The tetrahydroazepinone pharmacophore is a component of many interesting compounds, including severa...
Tsitsikammamines are marine alkaloids whose structure is based on the pyrroloiminoquinone scaffold. ...
A series of pyrrolic analogs and two series of regioisomeric pyrazolic analogs of the marine alkaloi...
The marine alkaloids Wakayin and Tsitsikammamine belong to the 1,3,4,5-tetrahydropyrrolo [4,3,2-de] ...
A series of pyrrolic analogs and two series of regioisomeric pyrazolic analogs of the marine alkaloi...
Indoleamine 2,3-dioxygenase (IDO1) and tryptophane 2,3-dioxygenase (TDO) are two heme-containing enz...
International audienceThis work describes the synthesis and biological evaluation of a new heterocyc...
Pyrroloiminoquinones are a group of cytotoxic alkaloids most commonly isolated from marine sponges. ...
Marine organisms have proven to be a promising source of new compounds with activity against tumor c...
Synthesis of 10 pyrroloiminoquinone derivatives is presented. The strategy is based around the elabo...