Nowadays, organizations rely more and more on information systems to collect, manipulate, and exchange their relevant and sensitive data. In these systems, security plays a vital role. Indeed, any security breach may cause serious consequences, even destroy an organization's reputation. Hence, sufficient precautions should be taken into account. Moreover, it is well recognized that the earlier an error is discovered, the easier and cheaper it is debugged. The objective of this thesis is to define adequate security policies since the early development phases and ensure their correct deployment on a given technological infrastructure. Our approach starts by specifying a set of security requirements, i.e. static and dynamic rules, along with t...