Add to ORKGInternational audienceSjögren's syndrome is a common autoimmune disease (affecting ∼0.7% of European Americans) that typically presents as keratoconjunctivitis sicca and xerostomia. Here we report results of a large-scale association study of Sjögren's syndrome. In addition to strong association within the human leukocyte antigen (HLA) region at 6p21 (Pmeta = 7.65 × 10(-114)), we establish associations with IRF5-TNPO3 (Pmeta = 2.73 × 10(-19)), STAT4 (Pmeta = 6.80 × 10(-15)), IL12A (Pmeta = 1.17 × 10(-10)), FAM167A-BLK (Pmeta = 4.97 × 10(-10)), DDX6-CXCR5 (Pmeta = 1.10 × 10(-8)) and TNIP1 (Pmeta = 3.30 × 10(-8)). We also observed suggestive associations (Pmeta < 5 × 10(-5)) with variants in 29 other regions, including TNFAIP3, PTTG1, PRDM1, ...
Background: Multiple autoimmune syndrome (MAS), an extreme phenotype of autoimmune disorders, is a v...
Sjögren's syndrome (SS) is a chronic autoimmune condition characterized by autoantibody production, ...
Sjögren's syndrome (SS) is a late-onset chronic autoimmune disease (AID) affecting the exocrine glan...
International audienceSjögren's syndrome is a common autoimmune disease (affecting ∼0.7% of European...
Sjögren's syndrome is a common autoimmune disease (affecting ∼0.7% of European Americans) that typic...
Sjögren's disease is a complex autoimmune disease with twelve established susceptibility loci. This ...
Sjögren’s disease is a complex autoimmune disease with twelve established susceptibility loci. This ...
Sjögren's disease is a complex autoimmune disease with twelve established susceptibility loci. This ...
Sjögren's syndrome (SS) is a chronic autoimmune condition characterized by autoantibody production, ...
Sjögren\u27s disease is a complex autoimmune disease with twelve established susceptibility loci. Th...
Sjogren's disease is a complex autoimmune disease with twelve established susceptibility loci. This ...
Sjogren's syndrome (SS), a chronic autoimmune disease, typically causes or involves inflammation in ...
ObjectiveThe Sjögren's International Collaborative Clinical Alliance (SICCA) is an international dat...
Sjogren's syndrome (SS), a chronic autoimmune disease, typically causes or involves inflammatio...
Sjögren’s syndrome (SS) is a chronic autoimmune condition characterized by autoantibody production, ...
Background: Multiple autoimmune syndrome (MAS), an extreme phenotype of autoimmune disorders, is a v...
Sjögren's syndrome (SS) is a chronic autoimmune condition characterized by autoantibody production, ...
Sjögren's syndrome (SS) is a late-onset chronic autoimmune disease (AID) affecting the exocrine glan...
International audienceSjögren's syndrome is a common autoimmune disease (affecting ∼0.7% of European...
Sjögren's syndrome is a common autoimmune disease (affecting ∼0.7% of European Americans) that typic...
Sjögren's disease is a complex autoimmune disease with twelve established susceptibility loci. This ...
Sjögren’s disease is a complex autoimmune disease with twelve established susceptibility loci. This ...
Sjögren's disease is a complex autoimmune disease with twelve established susceptibility loci. This ...
Sjögren's syndrome (SS) is a chronic autoimmune condition characterized by autoantibody production, ...
Sjögren\u27s disease is a complex autoimmune disease with twelve established susceptibility loci. Th...
Sjogren's disease is a complex autoimmune disease with twelve established susceptibility loci. This ...
Sjogren's syndrome (SS), a chronic autoimmune disease, typically causes or involves inflammation in ...
ObjectiveThe Sjögren's International Collaborative Clinical Alliance (SICCA) is an international dat...
Sjogren's syndrome (SS), a chronic autoimmune disease, typically causes or involves inflammatio...
Sjögren’s syndrome (SS) is a chronic autoimmune condition characterized by autoantibody production, ...
Background: Multiple autoimmune syndrome (MAS), an extreme phenotype of autoimmune disorders, is a v...
Sjögren's syndrome (SS) is a chronic autoimmune condition characterized by autoantibody production, ...
Sjögren's syndrome (SS) is a late-onset chronic autoimmune disease (AID) affecting the exocrine glan...