International audienceIt is argued in the life-oriented approach that travel behavior affects life choice and vice versa with resulting impacts on quality of life (QOL). By deepening the analysis of interdependences between daily mobility and life event (relocation) and their relationships with QOL, this article focuses on two challenges. It aims at analyzing how these life events first, encourage travel behavior changes, especially mode choice, and second, improve or decrease people’s QOL. By radically changing living context and built environment, relocation also affects routine and satisfaction. These relationships are investigated in the Luxembourg cross-border area, where great differences related to real estate price encourage residen...