Diabetic retinopathy (DR) is a major complication of diabetes, characterized by extensive vascular pathology leading to vision loss. Neuronal suffering and death are also present in the diabetic retina as a result of different molecular mechanisms that are compromised or modified in response to high glucose and that mainly include excitotoxicity, advanced glycation, inflammation and oxidative stress. Recent data indicate that the vascular changes may be secondary to damage of retinal neurons and that neurodegeneration is likely to play a primary role in the development of DR. Therefore, strategies based on neuroprotection may be exploited to treat DR. However, there are important limitations related to possible systemic side effects of neur...
Neovascular diseases of the posterior eye like age-related macular degeneration, proliferative diabe...
Despite the higher rate of blindness due to population aging, minimally invasive and selective drug ...
Pathologies affecting the optic nerve and the retina are one of the major causes of blindness. These...
Diabetic retinopathy (DR) is a major complication of diabetes, characterized by extensive vascular p...
The somatostatin analog octreotide (OCT) displays important neuroprotective and anti-angiogenic prop...
The clinical application of nanotechnology in medicine is promising for therapeutic, diagnostic, and...
Neurodegenerations are a complex pool of diseases united by a progressive loss of neuronal cells. Re...
ABSTRACT OF THE DISSERTATIONIntravitreal Therapeutic Nanoparticles for the Treatment of Posterior Se...
Nanoparticles are nanometer-scaled particles, and can be utilized in the form of nanocapsules, nanoc...
This work has elucidated the potential of bio-inspired lipid nanoparticles for targeted retinal drug...
AbstractWe are approaching a new era of retinal pharmacotherapy where new drugs are rapidly being wo...
Non-physiological angiogenesis is a mutual complication of the proliferative forms of diabetic retin...
Retinal degeneration refers to the pathological conditions affecting the ocular posterior segment, i...
Glaucoma and other optic neuropathies are characterized by a loss of retinal ganglion cells (RGCs), ...
We are witnessing an exponential increase in the use of different nanomaterials in a plethora of bio...
Neovascular diseases of the posterior eye like age-related macular degeneration, proliferative diabe...
Despite the higher rate of blindness due to population aging, minimally invasive and selective drug ...
Pathologies affecting the optic nerve and the retina are one of the major causes of blindness. These...
Diabetic retinopathy (DR) is a major complication of diabetes, characterized by extensive vascular p...
The somatostatin analog octreotide (OCT) displays important neuroprotective and anti-angiogenic prop...
The clinical application of nanotechnology in medicine is promising for therapeutic, diagnostic, and...
Neurodegenerations are a complex pool of diseases united by a progressive loss of neuronal cells. Re...
ABSTRACT OF THE DISSERTATIONIntravitreal Therapeutic Nanoparticles for the Treatment of Posterior Se...
Nanoparticles are nanometer-scaled particles, and can be utilized in the form of nanocapsules, nanoc...
This work has elucidated the potential of bio-inspired lipid nanoparticles for targeted retinal drug...
AbstractWe are approaching a new era of retinal pharmacotherapy where new drugs are rapidly being wo...
Non-physiological angiogenesis is a mutual complication of the proliferative forms of diabetic retin...
Retinal degeneration refers to the pathological conditions affecting the ocular posterior segment, i...
Glaucoma and other optic neuropathies are characterized by a loss of retinal ganglion cells (RGCs), ...
We are witnessing an exponential increase in the use of different nanomaterials in a plethora of bio...
Neovascular diseases of the posterior eye like age-related macular degeneration, proliferative diabe...
Despite the higher rate of blindness due to population aging, minimally invasive and selective drug ...
Pathologies affecting the optic nerve and the retina are one of the major causes of blindness. These...