Microbial products for use in cosmetics

Kozmetika je področje nenehnega napredka, novosti in izboljšav, saj smo ljudje vedno bolj pozorni na sestavo izdelkov, ki jih vnašamo na tak ali drugačen način v svoje telo. Posledično vse pogosteje posegamo po kozmetičnih produktih z naravnim izvorom, katerih virov je lahko več. V tem diplomskem delu je izpostavljeno področje kozmetike, kjer aktivne učinkovine predstavljajo mikrobni produkti in se na ta način povezuje z novejšimi biotehnološkimi pristopi. Prednost mikrobne produkcije je hitro pridobivanje produktov, enostavno gojenje mikroorganizmov in večja zmožnost prilagajanja procesa s spreminjanjem bioprocesnih parametrov. V nasprotju pa je pri pridobivanju produktov iz tkiv potrebno daljše časovno obdobje, da organizem sintetizira želeni produkt in na sam proces lahko manj vplivamo. Prihodnost pa se ne kaže le v produkciji učinkovin v mikroorganizmih, ki že naravno proizvajajo ta produkt, ampak s poznavanjem biosinteznih poti učinkovin vedno pogosteje tudi v rekombinantni produkciji.In cosmetic industry, there is a constant progress, innovations and improvements, since people are increasingly paying attention to the composition of products they use in everyday life. Therefore, there is an increase in use of cosmetic products with natural origin of numerous sources. In this thesis, cosmetic products including active components from microbial sources are presented. This connects cosmetic industry with modern biotechnology processes. The advantage of microbial production is the rapid production of products, easy cultivation of microorganisms and greater ability to adapt the process by changing bioprocess parameters. On the other hand in the case of isolation from tissues, longer period of time for the organism to synthesize product is required and we have less impact on the process. Therefore, the future is not only shown in the production of active compounds in microorganisms, which naturally produce them, but with knowledge of biosynthetic pathways of those compounds recombinant production is increasingly being used