The integration of cellular and molecular structural data is key to understanding the function of macromolecular assemblies and complexes in their in vivo context. Here we report on the outcomes of a workshop that discussed how to integrate structural data from a range of public archives. The workshop identified two main priorities: the development of tools and file formats to support segmentation (that is, the decomposition of a three-dimensional volume into regions that can be associated with defined objects), and the development of tools to support the annotation of biological structures.Peer reviewe
textLarge bio-molecular complexes (LBCs) are assemblies of dozens to thousands of structural/functi...
SummaryA detailed description of macromolecular assemblies in multiple conformational states can be ...
The approaches used by structural biologists evolve as they tackle the study of increasingly large, ...
The integration of cellular and molecular structural data is key to understanding the function of ma...
The integration of cellular and molecular structural data is key to understanding the function of ma...
The integration of cellular and molecular structural data is key to understanding the function of ma...
Structures of biomolecular systems are increasingly computed by integrative modeling. In this approa...
The functional units in cells are often assemblies of macromolecules, including proteins and nucleic...
Structural biology has paved the way for a ground-up description of biological systems, contributing...
We report the outcomes of the discussion initiated at the workshop entitled A 3D Cellular Context fo...
Structural biology is moving into a new era by shifting its focus from static structures of single p...
The reductionist program for biology foresees a progression of understanding that will span the gamu...
A detailed description of macromolecular assemblies in multiple conformational states can be very va...
A wide variety of experimental techniques can be used for understanding the precise molecular mechan...
Integrative structural biology combines data from multiple experimental techniques to generate compl...
textLarge bio-molecular complexes (LBCs) are assemblies of dozens to thousands of structural/functi...
SummaryA detailed description of macromolecular assemblies in multiple conformational states can be ...
The approaches used by structural biologists evolve as they tackle the study of increasingly large, ...
The integration of cellular and molecular structural data is key to understanding the function of ma...
The integration of cellular and molecular structural data is key to understanding the function of ma...
The integration of cellular and molecular structural data is key to understanding the function of ma...
Structures of biomolecular systems are increasingly computed by integrative modeling. In this approa...
The functional units in cells are often assemblies of macromolecules, including proteins and nucleic...
Structural biology has paved the way for a ground-up description of biological systems, contributing...
We report the outcomes of the discussion initiated at the workshop entitled A 3D Cellular Context fo...
Structural biology is moving into a new era by shifting its focus from static structures of single p...
The reductionist program for biology foresees a progression of understanding that will span the gamu...
A detailed description of macromolecular assemblies in multiple conformational states can be very va...
A wide variety of experimental techniques can be used for understanding the precise molecular mechan...
Integrative structural biology combines data from multiple experimental techniques to generate compl...
textLarge bio-molecular complexes (LBCs) are assemblies of dozens to thousands of structural/functi...
SummaryA detailed description of macromolecular assemblies in multiple conformational states can be ...
The approaches used by structural biologists evolve as they tackle the study of increasingly large, ...