Add to ORKGVesico-ureteral reflux (VUR) is a major contributing factor to end-stage renal disease in paediatric patients. Primary VUR is a familial disorder, but little is known about its genetic causes. To investigate the involvement of 12 functional candidate genes and two reported loci in VUR, we performed a linkage study in four large, Dutch, multi-generational families with multiple affected individuals. We were unable to detect linkage to any of the genes and loci and could exclude the GDNF, RET, SLIT2, SPRY1, PAX2, AGTR2, UPK1A and UPK3A genes and the 1p13 and 20p13 loci from linkage to VUR. Our results provide further evidence that there appears to be genetic heterogeneity in VUR
Chronic renal failure and end stage renal disease (ESRD) can be life-threatening conditions. In a si...
Vesicoureteral reflux (VUR) is the most common disease of the urinary tract in children. In order to...
Vesicoureteral reflux (VUR) is the retrograde passage of urine from the bladder to the upper urinary...
Vesico-ureteral reflux (VUR) is a major contributing factor to end-stage renal disease in paediatri...
Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urinary trac...
Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urinary trac...
<div><p>Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urin...
Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urinary trac...
Vesicoureteral reflux (VUR) is a common congenital anomaly with a high risk of recurrent urinary tra...
Primary vesicoureteric reflux (VUR) affects 1%–2% of whites, and reflux nephropathy (RN) causes up t...
Primary vesicoureteric reflux (VUR) is one of the more common genetic disorders. Little is yet known...
Vesicoureteral reflux (VUR) is a common, familial genitourinary disorder, and a major cause of pedia...
Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urinary trac...
Chronic renal failure and end stage renal disease (ESRD) can be life-threatening conditions. In a si...
Vesicoureteral reflux (VUR) is the most common disease of the urinary tract in children. In order to...
Vesicoureteral reflux (VUR) is the retrograde passage of urine from the bladder to the upper urinary...
Vesico-ureteral reflux (VUR) is a major contributing factor to end-stage renal disease in paediatri...
Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urinary trac...
Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urinary trac...
<div><p>Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urin...
Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urinary trac...
Vesicoureteral reflux (VUR) is a common congenital anomaly with a high risk of recurrent urinary tra...
Primary vesicoureteric reflux (VUR) affects 1%–2% of whites, and reflux nephropathy (RN) causes up t...
Primary vesicoureteric reflux (VUR) is one of the more common genetic disorders. Little is yet known...
Vesicoureteral reflux (VUR) is a common, familial genitourinary disorder, and a major cause of pedia...
Vesico-ureteral reflux (VUR) is the retrograde passage of urine from the bladder to the urinary trac...
Chronic renal failure and end stage renal disease (ESRD) can be life-threatening conditions. In a si...
Vesicoureteral reflux (VUR) is the most common disease of the urinary tract in children. In order to...
Vesicoureteral reflux (VUR) is the retrograde passage of urine from the bladder to the upper urinary...