Within the past decade a large repertoire of cellular oncogenes has been implicated in the genesis of many types of cancers. These oncogenes all function to promote the neoplastic growth of cells in which they act. Indeed, they all appear to derive from normal cell genes, proto-oncogenes, which act to stimulate normal cell proliferation. During this period, evidence has also been presented to suggest that elements that normally function to inhibit cell proliferation are also playing a role in the process of carcinogenesis. For instance, in a number of distinct types of tumors it was found that genetic material from specific chromosomal loci was absent in tumor DNAs, but present in the adjacent normal cell DNA. This indicates that l...
Oncogenes were first described as the genes of DNA tumor viruses responsible for in vivo and in vitr...
Oncogenes were first described as the genes of DNA tumor viruses responsible for in vivo and in vitr...
In the multi-factorial etiology of organ-site cancers by suspect human chemical carcinogens, oncogen...
Within the past decade a large repertoire of cellular oncogenes has been implicated in the genesis ...
A genetic basis for the development of cancer has been hypothesized for nearly a century and has bee...
In the recent past, a considerable amount of scientific literature has revealed impressive mechanism...
Cancer cells contain genetic damage of two sorts (Bishop 1991): dominant, with targets known as prot...
In principle, an oncogene is a cellular gene (proto-oncogene) that is dysfunctional, due to mutation...
Experimentalstudiesover the pastdecade have identified30 or so cellular,genes as potential oncogenes...
In the recent past, a considerable amount of scientific literature has revealed impressive mechanism...
In the recent past, a considerable amount of scientific literature has revealed impressive mechanism...
All vertebrates possess a series of genes which are homologs of the oncogenic genes of acute transfo...
Some observations on cellular senescence are discussed regarding the possibility that the postulated...
Tumour suppressor genes are a class of genes that have a crucial role in the genesis of neoplasia. T...
Oncogenes were first described as the genes of DNA tumor viruses responsible for in vivo and in vitr...
Oncogenes were first described as the genes of DNA tumor viruses responsible for in vivo and in vitr...
Oncogenes were first described as the genes of DNA tumor viruses responsible for in vivo and in vitr...
In the multi-factorial etiology of organ-site cancers by suspect human chemical carcinogens, oncogen...
Within the past decade a large repertoire of cellular oncogenes has been implicated in the genesis ...
A genetic basis for the development of cancer has been hypothesized for nearly a century and has bee...
In the recent past, a considerable amount of scientific literature has revealed impressive mechanism...
Cancer cells contain genetic damage of two sorts (Bishop 1991): dominant, with targets known as prot...
In principle, an oncogene is a cellular gene (proto-oncogene) that is dysfunctional, due to mutation...
Experimentalstudiesover the pastdecade have identified30 or so cellular,genes as potential oncogenes...
In the recent past, a considerable amount of scientific literature has revealed impressive mechanism...
In the recent past, a considerable amount of scientific literature has revealed impressive mechanism...
All vertebrates possess a series of genes which are homologs of the oncogenic genes of acute transfo...
Some observations on cellular senescence are discussed regarding the possibility that the postulated...
Tumour suppressor genes are a class of genes that have a crucial role in the genesis of neoplasia. T...
Oncogenes were first described as the genes of DNA tumor viruses responsible for in vivo and in vitr...
Oncogenes were first described as the genes of DNA tumor viruses responsible for in vivo and in vitr...
Oncogenes were first described as the genes of DNA tumor viruses responsible for in vivo and in vitr...
In the multi-factorial etiology of organ-site cancers by suspect human chemical carcinogens, oncogen...