B-cell lymphoma gene (BCL-6) upregulation contributes to immortalization of mouse embryo fibroblast and primary B cells via upregulation of cyclin D1. As cyclin D1 overexpression is a common phenomenon in different cancers, BCL-6 protein overexpression may not be restricted to lymphomas. In this study, expression of BCL-6 was investigated by immunohistochemistry on paraffin-embedded specimens from 150 breast cancer patients and 10 specimens of normal breast tissue. The results showed BCL-6 overexpression (X10% of cells) in 24/150 (16%) breast cancer patients, whereas in normal breast low expression (o1%) of BCL-6 was observed. In linear regression analysis BCL-6 expression was associated with cyclin D1 (r=0.197, P=0.016). Further, in v2...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
B-cell lymphoma gene (BCL-6) upregulation contributes to immortalization of mouse embryo fibroblast ...
Inappropriate expression or activation of transcription factors can drive patterns of gene expressio...
Introduction: BRCA1 is involved in numerous essential processes in the cell, and the effects of BRCA...
Introduction: BRCA1 is involved in numerous essential processes in the cell, and the effects of BRCA...
Introduction: BRCA1 is involved in numerous essential processes in the cell, and th...
Appropriately timed proliferation, differentiation and apoptosis are essential to the normal functio...
The expression pattern of the BCL-6 transcription factor has been assessed in normal and neoplastic ...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
The results presented identify the first genetic lesion associated with DLCL, the most clinically re...
The results presented identify the first genetic lesion associated with DLCL, the most clinically re...
The results presented identify the first genetic lesion associated with DLCL, the most clinically re...
The results presented identify the first genetic lesion associated with DLCL, the most clinically re...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
B-cell lymphoma gene (BCL-6) upregulation contributes to immortalization of mouse embryo fibroblast ...
Inappropriate expression or activation of transcription factors can drive patterns of gene expressio...
Introduction: BRCA1 is involved in numerous essential processes in the cell, and the effects of BRCA...
Introduction: BRCA1 is involved in numerous essential processes in the cell, and the effects of BRCA...
Introduction: BRCA1 is involved in numerous essential processes in the cell, and th...
Appropriately timed proliferation, differentiation and apoptosis are essential to the normal functio...
The expression pattern of the BCL-6 transcription factor has been assessed in normal and neoplastic ...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
The results presented identify the first genetic lesion associated with DLCL, the most clinically re...
The results presented identify the first genetic lesion associated with DLCL, the most clinically re...
The results presented identify the first genetic lesion associated with DLCL, the most clinically re...
The results presented identify the first genetic lesion associated with DLCL, the most clinically re...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...
BCL-6 is a novel proto-oncogene that codes for a zinc-finger protein sharing homologies with many tr...