LDL receptor-related protein (LRP) is a multifunctional cell surface receptor that is expressed in many cell types. It is able to bind numerous structurally unrelated ligands. This thesis describes four novel functions of LRP in different cell types. β2-integrins are heterodimeric proteins present at the cell surface of leukocytes. They are involved in various processes, like leukocyte adhesion to the vascular wall. We reported that LRP directly bound to the α-subunit of β2-integrins. Upon activation, β2-integrins form clusters in rafts of monocytes to increase the avidity for its ligands. LRP was co-immunoprecipitated with β2-integrins in the raft fraction of both naïve and stimulated monocytes. In addition, LRP colocalized with β2-integ...
AbstractLDL receptor related protein (LRP) is a ubiquitously expressed cell surface receptor that bi...
Elevated levels of low-density lipoprotein (LDL) and its derivative lipoprotein(a) (Lp(a)) in the bl...
Within the circulation, cholesterol is transported by lipoprotein particles and is taken up by cells...
The low density Lipoprotein receptor-related protein (LRP) has been localized in human brain at the ...
Low-density lipoprotein receptor-related protein-1 (LRP1) is an endocytic receptor for numerous prot...
Low-density lipoprotein receptor–related protein-1 (LRP1) is an endocytic receptor for numerous prot...
Low density lipoprotein receptor-related protein 1 (LRP1) is a ubiquitously expressed cell surface r...
The low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional cell surface rece...
Low density lipoprotein receptor-related protein (LRP) 1 modulates cell adhesion and motility under ...
The extracellular matrix (ECM) is a biological substrate composed of collagens, proteoglycans and gl...
Expression of molecules involved in lipid homeostasis such as the low density lipoprotein receptor (...
LDL Receptor-related Protein-1 (LRP1) is an endocytic receptor for diverse ligands. In neurons and n...
The low-density lipoprotein (LDL) receptor-related protein (LRP) is a member of the LDL receptor fam...
LDL Receptor-related Protein-1 (LRP1) is an endocytic receptor for diverse ligands. In neurons and n...
Low-density lipoprotein receptor-related protein-associated protein 1 (LRPAP1), also known as recept...
AbstractLDL receptor related protein (LRP) is a ubiquitously expressed cell surface receptor that bi...
Elevated levels of low-density lipoprotein (LDL) and its derivative lipoprotein(a) (Lp(a)) in the bl...
Within the circulation, cholesterol is transported by lipoprotein particles and is taken up by cells...
The low density Lipoprotein receptor-related protein (LRP) has been localized in human brain at the ...
Low-density lipoprotein receptor-related protein-1 (LRP1) is an endocytic receptor for numerous prot...
Low-density lipoprotein receptor–related protein-1 (LRP1) is an endocytic receptor for numerous prot...
Low density lipoprotein receptor-related protein 1 (LRP1) is a ubiquitously expressed cell surface r...
The low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional cell surface rece...
Low density lipoprotein receptor-related protein (LRP) 1 modulates cell adhesion and motility under ...
The extracellular matrix (ECM) is a biological substrate composed of collagens, proteoglycans and gl...
Expression of molecules involved in lipid homeostasis such as the low density lipoprotein receptor (...
LDL Receptor-related Protein-1 (LRP1) is an endocytic receptor for diverse ligands. In neurons and n...
The low-density lipoprotein (LDL) receptor-related protein (LRP) is a member of the LDL receptor fam...
LDL Receptor-related Protein-1 (LRP1) is an endocytic receptor for diverse ligands. In neurons and n...
Low-density lipoprotein receptor-related protein-associated protein 1 (LRPAP1), also known as recept...
AbstractLDL receptor related protein (LRP) is a ubiquitously expressed cell surface receptor that bi...
Elevated levels of low-density lipoprotein (LDL) and its derivative lipoprotein(a) (Lp(a)) in the bl...
Within the circulation, cholesterol is transported by lipoprotein particles and is taken up by cells...