Fetal fibronectin status and cervical length in women with threatened preterm labor and the effectiveness of maintenance tocolysis
- Roos, C.
- Vis, J.Y.
- Scheepers, H.C.
- Bloemenkamp, K.W.
- Duvekot, H.J.
- Eyck, J. van
- Groot, C. de
- Kok, J.H.
- Opmeer, B.C.
- Oudijk, M.A.
- Papatsonis, D.N.
- Porath, M.M.
- Sollie, K.
- Spaanderman, M.E.A.
- Lotgering, F.K.
- Post, J.A. van der
- Mol, B.W.
DOIAbstract
OBJECTIVE: To assess the effect of maintenance tocolysis in women who are at high or low risk for preterm delivery according to fetal fibronectin (fFN) status and cervical length (CL). STUDY DESIGN: We compared the risk of preterm delivery in fFN pos and fFN neg women and in women with a CL /=15 mm, by using the Cox regression. Differences between the effectiveness of maintenance tocolysis in high- and low-risk women were assessed by using an interaction term. RESULTS: 122 fFN tests were taken, of which 50 were fFN pos. CL was measured in 236 women, of whom 52 women had a CL <15 mm. The median gestational age at delivery was lower in fFN pos women; fFN pos women had a higher hazard for preterm delivery at any point of time (HR 4.7; 95% CI 2...
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