textabstractBackground: Balloon injury (BI) of the rat carotid artery (CCA) is widely used to study intimal hyperplasia (IH) and decrease in lumen diameter (LD), but CCA's small diameter impedes the evaluation of endovascular therapies. Therefore, we validated BI in the aorta (AA) and iliac artery (CIA) to compare it with CCA. Methods: Rats underwent BI or a sham procedure (control). Light microscopic evaluation was performed either directly or at 1, 2, 3, 4 and 16 weeks follow-up. The area of IH and the change in LD (LD at 16 weeks minus LD post BI) were compared. Results: In the BI-groups the area of IH increased to 0.14 ± 0.08 mm2 (CCA), 0.14 ± 0.03 mm2 (CIA) and 0.12 ± 0.04 mm2 (AA) at 16 weeks (NS). The LD decreased with 0.49 ± 0.07 mm...
The objective of this study was to clarify the relative roles of medial versus luminal factors in th...
<p>(<b>A, B</b>) Seven-week-old SD rats (200 g) were treated with the appropriate substance by i.p. ...
This study assessed the blood flow and histological changes of an animal model of arteriovenous malf...
textabstractBACKGROUND: Balloon injury (BI) of the rat carotid artery (CCA) is widely used to ...
Background: Balloon injury (BI) of the rat carotid artery (CCA) is widely used to study intimal hype...
We induced arterial balloon injuries twice via a hyperdiastolic balloon catheter inserted into the c...
Treatments to prevent intimai hyperplasia, effective in balloon-injured rat arteries, have been disa...
The best animal angioplasty model is the porcine model, which is expensive and not available in all ...
Objective: Invasive coronary interventions can fail due to intimal hyperplasia and restenosis. Endot...
A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment...
Purpose: Our purpose was to determine whether exposure to cigarette smoke increases the development ...
The use of animal models is essential for a better understanding of MH, one major cause for arterial...
AbstractPurpose: We sought to determine whether low-dose radiation can inhibit neointimal hyperplasi...
The objective of this study was to clarify the relative roles of medial versus luminal factors in th...
Appropriately sized arteries in small animals may be possible models for studying the remodeling pro...
The objective of this study was to clarify the relative roles of medial versus luminal factors in th...
<p>(<b>A, B</b>) Seven-week-old SD rats (200 g) were treated with the appropriate substance by i.p. ...
This study assessed the blood flow and histological changes of an animal model of arteriovenous malf...
textabstractBACKGROUND: Balloon injury (BI) of the rat carotid artery (CCA) is widely used to ...
Background: Balloon injury (BI) of the rat carotid artery (CCA) is widely used to study intimal hype...
We induced arterial balloon injuries twice via a hyperdiastolic balloon catheter inserted into the c...
Treatments to prevent intimai hyperplasia, effective in balloon-injured rat arteries, have been disa...
The best animal angioplasty model is the porcine model, which is expensive and not available in all ...
Objective: Invasive coronary interventions can fail due to intimal hyperplasia and restenosis. Endot...
A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment...
Purpose: Our purpose was to determine whether exposure to cigarette smoke increases the development ...
The use of animal models is essential for a better understanding of MH, one major cause for arterial...
AbstractPurpose: We sought to determine whether low-dose radiation can inhibit neointimal hyperplasi...
The objective of this study was to clarify the relative roles of medial versus luminal factors in th...
Appropriately sized arteries in small animals may be possible models for studying the remodeling pro...
The objective of this study was to clarify the relative roles of medial versus luminal factors in th...
<p>(<b>A, B</b>) Seven-week-old SD rats (200 g) were treated with the appropriate substance by i.p. ...
This study assessed the blood flow and histological changes of an animal model of arteriovenous malf...