Add to ORKGCinchona alkaloids have a long history as being a powerful medicine against malaria. Since a relative short period (about 50 years) chemist have also used these alkaloids as chiral catalyst for a wide variety of asymmetric transformations. Especially since the beginning of this century, when strong hydrogen bond donors were introduced improving the catalyst activity and selectivity. The research described in this thesis focuses on the use of Cinchona alkaloids as non-covalent bifunctional organocatalysts. Two subjects will be addressed: the development of new asymmetric conjugate additions yielding products that can be used in peptide chemistry and the second part is focused on the synthesis of novel analogues of Cinchona alkaloids. The sec...
Cooperative catalysis, inspired by the early findings on enzymatic activation, is a fast growing res...
Nonquaternised Cinchona Alkaloid Derivatives as Asymmetric Organocatalysts for Carbon-Carbon Bond-Fo...
The introduction of fluorine into molecules is an important tool in the agrochemical and pharmaceuti...
This article reviews the applications of cinchona alkaloids as asymmetric catalysts. In the last few...
THESIS 10151Over the past three decades, the synthesis of enantiomerically pure products became a ma...
Cinchona alkaloids comprising quinine, quinidine, cinchonidine and cinchonine as the major members c...
THESIS 9127The design and synthesis of small organic molecules which effectively mimic the hydrogen-...
Remarkable progress in the area of asymmetric organocatalysis has been achieved in the last decades....
Cinchona alkaloid-derived chiral catalysts represent one of the most widely applied classes of organ...
The preparation of new organocatalysts for asymmetric syntheses has become a key stage of enantiosel...
Cinchona alkaloids with a free 6'-OH functionality are being increasingly used within asymmetric org...
none6noneP. Melchiorre; A. Carlone; A. Cavalli; P. Ricci; L. Sambri; G. BartoliP. Melchiorre; A. Car...
Three novel subclasses of cinchonidine derivatives coupled to diverse amino acids were prepared in v...
A new asymmetric synthesis of 2-substituted chiral chromanes has been achieved. The key step is the ...
This bachelor thesis deals with the preparation of C−9 Cinchona alkaloid derivatives, which are used...
Cooperative catalysis, inspired by the early findings on enzymatic activation, is a fast growing res...
Nonquaternised Cinchona Alkaloid Derivatives as Asymmetric Organocatalysts for Carbon-Carbon Bond-Fo...
The introduction of fluorine into molecules is an important tool in the agrochemical and pharmaceuti...
This article reviews the applications of cinchona alkaloids as asymmetric catalysts. In the last few...
THESIS 10151Over the past three decades, the synthesis of enantiomerically pure products became a ma...
Cinchona alkaloids comprising quinine, quinidine, cinchonidine and cinchonine as the major members c...
THESIS 9127The design and synthesis of small organic molecules which effectively mimic the hydrogen-...
Remarkable progress in the area of asymmetric organocatalysis has been achieved in the last decades....
Cinchona alkaloid-derived chiral catalysts represent one of the most widely applied classes of organ...
The preparation of new organocatalysts for asymmetric syntheses has become a key stage of enantiosel...
Cinchona alkaloids with a free 6'-OH functionality are being increasingly used within asymmetric org...
none6noneP. Melchiorre; A. Carlone; A. Cavalli; P. Ricci; L. Sambri; G. BartoliP. Melchiorre; A. Car...
Three novel subclasses of cinchonidine derivatives coupled to diverse amino acids were prepared in v...
A new asymmetric synthesis of 2-substituted chiral chromanes has been achieved. The key step is the ...
This bachelor thesis deals with the preparation of C−9 Cinchona alkaloid derivatives, which are used...
Cooperative catalysis, inspired by the early findings on enzymatic activation, is a fast growing res...
Nonquaternised Cinchona Alkaloid Derivatives as Asymmetric Organocatalysts for Carbon-Carbon Bond-Fo...
The introduction of fluorine into molecules is an important tool in the agrochemical and pharmaceuti...